Celecoxib and Sick sinus syndrome - a phase IV clinical study of FDA data
Summary:
Sick sinus syndrome is reported as a side effect among people who take Celecoxib (celecoxib), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Plavix, and have High blood pressure.
The phase IV clinical study analyzes which people have Sick sinus syndrome when taking Celecoxib. It is created by eHealthMe based on reports of 37,974 people who have side effects when taking Celecoxib from the FDA, and is updated regularly.
What is Celecoxib?
Celecoxib has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 38,217 Celecoxib users. Check the latest studies of Celecoxib.
What is Sick sinus syndrome?
Sick sinus syndrome (a collection of heart rhythm disorders) is found to be associated with 580 drugs and 842 conditions by eHealthMe. Check the latest studies of Sick sinus syndrome.
37,974 people reported to have side effects when taking Celecoxib.
Among them, 19 people (0.05%) have Sick sinus syndrome.

Among these 19 people:
How long have people been on Celecoxib when they have Sick sinus syndrome? *
- < 1 month: 0.0 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 50 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Sick sinus syndrome when taking Celecoxib? *
- female: 94.74 %
- male: 5.26 %
What is the age of people who have Sick sinus syndrome when taking Celecoxib? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
What are other drugs people take besides Celecoxib? *
- Plavix: 7 people, 36.84%
- Clopidogrel: 6 people, 31.58%
- Digoxin: 6 people, 31.58%
- Celebrex: 5 people, 26.32%
- Prednisolone: 5 people, 26.32%
- Pioglitazone: 5 people, 26.32%
- Amlodipine Besylate: 5 people, 26.32%
- Cefdinir: 5 people, 26.32%
- Allopurinol: 5 people, 26.32%
- Hydrochlorothiazide: 5 people, 26.32%
What are other side effects people have besides Sick sinus syndrome? *
- Dyspnea (difficult or laboured breathing): 6 people, 31.58%
- Hypotension (abnormally low blood pressure): 6 people, 31.58%
- Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 6 people, 31.58%
- Diastolic Dysfunction: 5 people, 26.32%
- Heart Rate Decreased: 5 people, 26.32%
- Heart Rate Irregular: 5 people, 26.32%
- Visual Field Defect: 5 people, 26.32%
- Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 4 people, 21.05%
- Abdominal Pain: 4 people, 21.05%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 15.79%
What are the existing conditions these people have? *
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 21.05%
- High Blood Pressure: 4 people, 21.05%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.53%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 5.26%
- Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 5.26%
- Back Pain: 1 person, 5.26%
- Bipolar Disorder (mood disorder): 1 person, 5.26%
- Breast Cancer Metastatic: 1 person, 5.26%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Celecoxib and have Sick sinus syndrome?
- Check whether Sick sinus syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Celecoxib:
- Celecoxib (38,217 reports)
Sick sinus syndrome treatments and more:
- Sick sinus syndrome (4,617 reports)
How severe was Sick sinus syndrome and when was it recovered:
Expand to all the drugs that have ingredients of celecoxib:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Celecoxib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Sick sinus syndrome:
- Sick sinus syndrome (580 drugs)
Browse all the conditions that are associated with Sick sinus syndrome:
- Sick sinus syndrome (842 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on celecoxib (the active ingredients of Celecoxib) and Celecoxib (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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