Cevimeline and Intervertebral disc protrusion - a phase IV clinical study of FDA data

Summary:

Intervertebral disc protrusion is reported as a side effect among people who take Cevimeline (cevimeline hydrochloride), especially for people who are female, 50-59 old, also take Xyrem, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Intervertebral disc protrusion when taking Cevimeline. It is created by eHealthMe based on reports of 1,450 people who have side effects when taking Cevimeline from the FDA, and is updated regularly.

What is Cevimeline?

Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.

What is Intervertebral disc protrusion?

Intervertebral disc protrusion (spinal disc protrusion) is found to be associated with 1,531 drugs and 1,305 conditions by eHealthMe. Check the latest studies of Intervertebral disc protrusion.

On Jul, 26, 2026

1,450 people reported to have side effects when taking Cevimeline.
Among them, 12 people (0.83%) have Intervertebral disc protrusion.

Could Cevimeline cause Intervertebral disc protrusion?

Among these 12 people:

What is the gender of people who have Intervertebral disc protrusion when taking Cevimeline? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Intervertebral disc protrusion when taking Cevimeline? *

What are other drugs people take besides Cevimeline? *

What are other side effects people have besides Intervertebral disc protrusion? *

Joint Pain: 5 people, 41.67%
Therapeutic Response Unexpected: 3 people, 25.00%
Neuralgia (pain in one or more nerves): 3 people, 25.00%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 25.00%
Blood Copper Increased: 3 people, 25.00%
Fatigue (feeling of tiredness): 3 people, 25.00%
Injection Site Pain: 3 people, 25.00%
Injection Site Erythema (redness at injection site): 2 people, 16.67%
Itching: 2 people, 16.67%
Pain: 2 people, 16.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 41.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 25.00%
Pain: 3 people, 25.00%
High Blood Cholesterol: 3 people, 25.00%
High Blood Pressure: 3 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
Insomnia (sleeplessness): 2 people, 16.67%
Thyroid Diseases: 2 people, 16.67%
Blood Glucose Decreased: 2 people, 16.67%
Gastric Disorder (disease of stomach): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cevimeline and have Intervertebral disc protrusion?

- Check whether Intervertebral disc protrusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cevimeline:

Cevimeline (1,480 reports)

Browse all side effects of Cevimeline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (1,531 drugs)

Browse all the conditions that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (1,305 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cevimeline hydrochloride (the active ingredients of Cevimeline) and Cevimeline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.