Chestnut and Chest pain - a phase IV clinical study of FDA data

Summary:

Chest pain is reported as a side effect among people who take Chestnut (horse chestnut), especially for people who are female, 60+ old, also take Vitamin D3, and have Primary immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Chest pain when taking Chestnut. It is created by eHealthMe based on reports of 517 people who have side effects when taking Chestnut from the FDA, and is updated regularly.

What is Chestnut?

Chestnut has active ingredients of horse chestnut. eHealthMe is studying from 538 Chestnut users. Check the latest studies of Chestnut.

What is Chest pain?

Chest pain is found to be associated with 3,461 drugs and 4,888 conditions by eHealthMe. Check the latest studies of Chest pain.

On Jul, 31, 2026

517 people reported to have side effects when taking Chestnut.
Among them, 16 people (3.09%) have Chest pain.

Among these 16 people:

What is the gender of people who have Chest pain when taking Chestnut? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Chest pain when taking Chestnut? *

What are other drugs people take besides Chestnut? *

What are other side effects people have besides Chest pain? *

High Blood Pressure: 7 people, 43.75%
Fatigue (feeling of tiredness): 7 people, 43.75%
Dehydration (dryness resulting from the removal of water): 5 people, 31.25%
Oedema Peripheral (superficial swelling): 5 people, 31.25%
Pain: 5 people, 31.25%
Peripheral Swelling: 5 people, 31.25%
Neoplasm Malignant (cancer tumour): 5 people, 31.25%
Cough: 5 people, 31.25%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 5 people, 31.25%
Hordeolum (small collection of pus (abscess) on the eyelid): 5 people, 31.25%

What are the existing conditions these people have? *

Primary Immunodeficiency Syndrome: 5 people, 31.25%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 25.00%
Varicose Vein (veins that have become enlarged and tortuous): 3 people, 18.75%
Stress And Anxiety: 3 people, 18.75%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 18.75%
High Blood Cholesterol: 3 people, 18.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Blood Glucose Increased: 3 people, 18.75%
Immunodeficiency Common Variable: 2 people, 12.50%
Wound: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Chestnut and have Chest pain?

- Check whether Chest pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chestnut:

Chestnut (538 reports)

Chest pain treatments and more:

Chest pain (363,501 reports)

Browse all side effects of Chestnut:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chest pain:

Chest pain (3,461 drugs)

Browse all the conditions that are associated with Chest pain:

Chest pain (4,888 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on horse chestnut (the active ingredients of Chestnut) and Chestnut (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.