Chestnut and Diarrhea aggravated - a phase IV clinical study of FDA data

Summary:

Diarrhea aggravated is reported as a side effect among people who take Chestnut (horse chestnut), especially for people who are female, 60+ old, also take Vitamin C, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Diarrhea aggravated when taking Chestnut. It is created by eHealthMe based on reports of 517 people who have side effects when taking Chestnut from the FDA, and is updated regularly.

What is Chestnut?

Chestnut has active ingredients of horse chestnut. eHealthMe is studying from 538 Chestnut users. Check the latest studies of Chestnut.

What is Diarrhea aggravated?

Diarrhea aggravated is found to be associated with 3,043 drugs and 1,265 conditions by eHealthMe. Check the latest studies of Diarrhea aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

517 people reported to have side effects when taking Chestnut.
Among them, 11 people (2.13%) have Diarrhea aggravated.

Could Chestnut cause Diarrhea aggravated?

Among these 11 people:

What is the gender of people who have Diarrhea aggravated when taking Chestnut? *

female: 100 %
male: 0.0 %

What is the age of people who have Diarrhea aggravated when taking Chestnut? *

What are other drugs people take besides Chestnut? *

What are other side effects people have besides Diarrhea aggravated? *

Abdominal Distension: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Vaginal Infection: 2 people, 18.18%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 18.18%
Abnormal Faeces (abnormal stool): 2 people, 18.18%
Hospitalisation: 2 people, 18.18%
Laboratory Test Abnormal: 2 people, 18.18%
Migraine (headache): 2 people, 18.18%
Nausea And Vomiting: 2 people, 18.18%
Abdominal Discomfort: 2 people, 18.18%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 27.27%
Multiple Myeloma (cancer of the plasma cells): 3 people, 27.27%
Wound: 1 person, 9.09%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 9.09%
Poor Peripheral Circulation: 1 person, 9.09%
Pituitary Tumor: 1 person, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%
Blood Pressure Abnormal: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Chestnut and have Diarrhea aggravated?

- Check whether Diarrhea aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chestnut:

Chestnut (538 reports)

Browse all side effects of Chestnut:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea aggravated:

Diarrhea aggravated (3,043 drugs)

Browse all the conditions that are associated with Diarrhea aggravated:

Diarrhea aggravated (1,265 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on horse chestnut (the active ingredients of Chestnut) and Chestnut (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.