Naproxen and Malic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Malic acid (alpha hydroxy acids). Common drug interactions include anaphylactic reaction among females.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Malic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,034 Naproxen users. Check the latest studies of Naproxen.

What is Malic acid?

Malic acid has active ingredients of alpha hydroxy acids. It is often used in fibromyalgia. eHealthMe is studying from 246 Malic acid users. Check the latest studies of Malic acid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

14 people who take Naproxen and Malic acid together, and have interactions are studied.

Naproxen and Malic acid drug interactions.

What are the common drug interactions of Naproxen and Malic Acid, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Anxiety
Pancreatitis (inflammation of pancreas)
Postoperative wound infection
Scleroderma (hard skin)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Urinary tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Dermatitis allergic (inflammation of the skin due allergic reaction)

male:

n/a

What are the common drug interactions of Naproxen and Malic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dermatitis allergic (inflammation of the skin due allergic reaction)
Fall
Dry eye (lack of adequate tears)
Hypersomnia (excessive daytime sleepiness (eds))
Immunodeficiency
Post procedural complication
Brain neoplasm (tumour of brain)
Brain stem syndrome
Haemochromatosis (body to absorb more iron than usual from food)
Neuralgia (pain in one or more nerves)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 100.00%
Drowsiness: 7 people, 50.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and Malic acid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously