Chlorhexidine gluconate and Parotid gland enlargement - a phase IV clinical study of FDA data

Summary:

Parotid gland enlargement is reported as a side effect among people who take Chlorhexidine gluconate (chlorhexidine gluconate), especially for people who are male, 60+ old, also take Diovan, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Parotid gland enlargement when taking Chlorhexidine gluconate. It is created by eHealthMe based on reports of 8,183 people who have side effects when taking Chlorhexidine gluconate from the FDA, and is updated regularly.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

What is Parotid gland enlargement?

Parotid gland enlargement is found to be associated with 200 drugs and 307 conditions by eHealthMe. Check the latest studies of Parotid gland enlargement.

On Jul, 16, 2026

8,183 people reported to have side effects when taking Chlorhexidine gluconate.
Among them, 16 people (0.2%) have Parotid gland enlargement.

Could Chlorhexidine gluconate cause Parotid gland enlargement?

Among these 16 people:

What is the gender of people who have Parotid gland enlargement when taking Chlorhexidine gluconate? *

female: 50 %
male: 50 %

What is the age of people who have Parotid gland enlargement when taking Chlorhexidine gluconate? *

What are other drugs people take besides Chlorhexidine gluconate? *

What are other side effects people have besides Parotid gland enlargement? *

Anaemia (lack of blood): 16 people, 100.00%
Pain In Jaw: 16 people, 100.00%
Osteomyelitis (infection of bone): 13 people, 81.25%
Cellulitis (infection under the skin): 13 people, 81.25%
Bone Disorder: 13 people, 81.25%
Hypoaesthesia (reduced sense of touch or sensation): 13 people, 81.25%
Weight Decreased: 12 people, 75.00%
Neuropathy Peripheral (surface nerve damage): 11 people, 68.75%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 9 people, 56.25%
Hypophagia (reduced food intake): 9 people, 56.25%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 50.00%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.25%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorhexidine gluconate and have Parotid gland enlargement?

- Check whether Parotid gland enlargement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorhexidine gluconate:

Chlorhexidine gluconate (8,233 reports)

Browse all side effects of Chlorhexidine gluconate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Parotid gland enlargement:

Parotid gland enlargement (200 drugs)

Browse all the conditions that are associated with Parotid gland enlargement:

Parotid gland enlargement (307 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Chlorhexidine gluconate) and Chlorhexidine gluconate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.