Chlorothiazide and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Chlorothiazide (chlorothiazide), especially for people who are male, 60+ old, also take Digoxin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Chlorothiazide. It is created by eHealthMe based on reports of 1,203 people who have side effects when taking Chlorothiazide from the FDA, and is updated regularly.

What is Chlorothiazide?

Chlorothiazide has active ingredients of chlorothiazide. eHealthMe is studying from 1,220 Chlorothiazide users. Check the latest studies of Chlorothiazide.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,954 drugs and 2,939 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On Aug, 11, 2026

1,203 people reported to have side effects when taking Chlorothiazide.
Among them, 13 people (1.08%) have Hyperkalemia.

Could Chlorothiazide cause Hyperkalemia?

Among these 13 people:

What is the gender of people who have Hyperkalemia when taking Chlorothiazide? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Hyperkalemia when taking Chlorothiazide? *

What are other drugs people take besides Chlorothiazide? *

What are other side effects people have besides Hyperkalemia? *

Blood Creatinine Increased: 6 people, 46.15%
Cellulitis (infection under the skin): 4 people, 30.77%
Weakness: 4 people, 30.77%
Nosebleed (bleeding from nose): 4 people, 30.77%
Anaemia (lack of blood): 4 people, 30.77%
Oedema Peripheral (superficial swelling): 4 people, 30.77%
Pain In Extremity: 4 people, 30.77%
Fluid Overload (too much fluid in the blood): 4 people, 30.77%
Fever: 3 people, 23.08%
Bundle Branch Block Right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 3 people, 23.08%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 23.08%
High Blood Pressure: 3 people, 23.08%
Dyslipidaemia (abnormal amount of lipids): 2 people, 15.38%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
Pneumonia Mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorothiazide and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorothiazide:

Chlorothiazide (1,220 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Chlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,954 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,939 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorothiazide (the active ingredients of Chlorothiazide) and Chlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.