Chondroitin and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Chondroitin (chondroitin sulfate), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Magnesium, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Chondroitin. It is created by eHealthMe based on reports of 3,822 people who have side effects when taking Chondroitin from the FDA, and is updated regularly.

What is Chondroitin?

Chondroitin has active ingredients of chondroitin sulfate. eHealthMe is studying from 3,959 Chondroitin users. Check the latest studies of Chondroitin.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,954 drugs and 2,940 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

3,822 people reported to have side effects when taking Chondroitin.
Among them, 12 people (0.31%) have Hyperkalemia.

Could Chondroitin cause Hyperkalemia?

Among these 12 people:

How long have people been on Chondroitin when they have Hyperkalemia? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 66.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperkalemia when taking Chondroitin? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Hyperkalemia when taking Chondroitin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 83.33 %

What are other drugs people take besides Chondroitin? *

  1. Magnesium: 4 people, 33.33%
  2. Lisinopril: 3 people, 25.00%
  3. Synthroid: 3 people, 25.00%
  4. Calcium: 3 people, 25.00%
  5. Azathioprine: 2 people, 16.67%
  6. Paxlovid: 2 people, 16.67%
  7. Prograf: 2 people, 16.67%
  8. Coreg: 2 people, 16.67%
  9. Prednisolone: 2 people, 16.67%
  10. Vesicare: 2 people, 16.67%

What are other side effects people have besides Hyperkalemia? *

  1. Diarrhea: 5 people, 41.67%
  2. Fall: 4 people, 33.33%
  3. Weakness: 3 people, 25.00%
  4. Acute Kidney Failure: 3 people, 25.00%
  5. Dizziness: 3 people, 25.00%
  6. Pain: 2 people, 16.67%
  7. Muscle Spasms (muscle contraction): 2 people, 16.67%
  8. Immunosuppressant Drug Level Increased: 2 people, 16.67%
  9. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 16.67%
  10. Feeling Hot: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Urge Incontinence (urinary incontinence): 2 people, 16.67%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 16.67%
  3. High Blood Pressure: 2 people, 16.67%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 16.67%
  5. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 8.33%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
  7. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 8.33%
  8. Insomnia (sleeplessness): 1 person, 8.33%
  9. Immunodeficiency Disorders: 1 person, 8.33%
  10. Gait Disturbance: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Chondroitin and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chondroitin:

Hyperkalemia treatments and more:

How severe was Hyperkalemia and when was it recovered:

Expand to all the drugs that have ingredients of chondroitin sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chondroitin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Browse all the conditions that are associated with Hyperkalemia:


How the study uses the data?

The study uses data from the FDA. It is based on chondroitin sulfate (the active ingredients of Chondroitin) and Chondroitin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: