Ciclosporin and Bacterial sepsis - a phase IV clinical study of FDA data

Summary:

Bacterial sepsis is reported as a side effect among people who take Ciclosporin (cyclosporine), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Methotrexate, and have Aplastic anemia.

The phase IV clinical study analyzes which people have Bacterial sepsis when taking Ciclosporin. It is created by eHealthMe based on reports of 3,560 people who have side effects when taking Ciclosporin from the FDA, and is updated regularly.

What is Ciclosporin?

Ciclosporin has active ingredients of cyclosporine. eHealthMe is studying from 3,571 Ciclosporin users. Check the latest studies of Ciclosporin.

What is Bacterial sepsis?

Bacterial sepsis is found to be associated with 435 drugs and 835 conditions by eHealthMe. Check the latest studies of Bacterial sepsis.

On Jul, 06, 2026

3,560 people reported to have side effects when taking Ciclosporin.
Among them, 12 people (0.34%) have Bacterial sepsis.

Could Ciclosporin cause Bacterial sepsis?

Among these 12 people:

How long have people been on Ciclosporin when they have Bacterial sepsis? *

What is the gender of people who have Bacterial sepsis when taking Ciclosporin? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Bacterial sepsis when taking Ciclosporin? *

What are other drugs people take besides Ciclosporin? *

Cyclophosphamide: 3 people, 25.00%
Methotrexate: 3 people, 25.00%
Busulfan: 2 people, 16.67%
Methylprednisolone Sodium Succinate: 2 people, 16.67%
Prednisolone: 2 people, 16.67%
Voriconazole: 2 people, 16.67%
Ursodeoxycholic Acid: 2 people, 16.67%
Amphotericin B: 1 person, 8.33%
Caspofungin Acetate: 1 person, 8.33%
Cefotaxime: 1 person, 8.33%

What are other side effects people have besides Bacterial sepsis? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 16.67%
Weakness: 1 person, 8.33%
Death: 1 person, 8.33%
Leukopenia (less number of white blood cells in blood): 1 person, 8.33%
Laryngitis Fungal (inflammation of the larynx due to fungal infection): 1 person, 8.33%
Klebsiella Sepsis (klebsiella causes a potentially fatal whole-body inflammation): 1 person, 8.33%
Idiopathic Pneumonia Syndrome (pneumonia-like symptoms): 1 person, 8.33%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 8.33%
Furuncle (infection of the hair follicle): 1 person, 8.33%
Fungal Sepsis (whole body infection by fungus): 1 person, 8.33%

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 16.67%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 16.67%
Aplastic Anemia: 2 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
Bone Marrow Failure: 1 person, 8.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ciclosporin and have Bacterial sepsis?

- Check whether Bacterial sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ciclosporin:

Ciclosporin (3,571 reports)

Browse all side effects of Ciclosporin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bacterial sepsis:

Bacterial sepsis (435 drugs)

Browse all the conditions that are associated with Bacterial sepsis:

Bacterial sepsis (835 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Ciclosporin) and Ciclosporin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.