Cimetidine and Bone loss - a phase IV clinical study of FDA data

Summary:

Bone loss is reported as a side effect among people who take Cimetidine (cimetidine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Atripla, and have Hiv infection.

The phase IV clinical study analyzes which people have Bone loss when taking Cimetidine. It is created by eHealthMe based on reports of 10,379 people who have side effects when taking Cimetidine from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Bone loss?

Bone loss is found to be associated with 695 drugs and 557 conditions by eHealthMe. Check the latest studies of Bone loss.



On Jul, 17, 2026

10,379 people reported to have side effects when taking Cimetidine.
Among them, 16 people (0.15%) have Bone loss.

Could Cimetidine cause Bone loss?

Among these 16 people:

How long have people been on Cimetidine when they have Bone loss? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bone loss when taking Cimetidine? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Bone loss when taking Cimetidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.33 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 25.0 %
  • 60+: 50.0 %

What are other drugs people take besides Cimetidine? *

  1. Truvada: 7 people, 43.75%
  2. Atripla: 7 people, 43.75%
  3. Biktarvy: 6 people, 37.50%
  4. Norvir: 6 people, 37.50%
  5. Bactrim: 6 people, 37.50%
  6. Vancomycin: 6 people, 37.50%
  7. Heparin: 5 people, 31.25%
  8. Epivir: 4 people, 25.00%
  9. Lyrica: 4 people, 25.00%
  10. Crestor: 4 people, 25.00%

What are other side effects people have besides Bone loss? *

  1. Pain: 13 people, 81.25%
  2. Stress And Anxiety: 11 people, 68.75%
  3. Emotional Distress: 11 people, 68.75%
  4. Bone Density Decreased: 9 people, 56.25%
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 8 people, 50.00%
  6. Osteoporosis (bones weak and more likely to break): 7 people, 43.75%
  7. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 7 people, 43.75%
  8. Depression: 7 people, 43.75%
  9. Nausea (feeling of having an urge to vomit): 6 people, 37.50%
  10. Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 31.25%

What are the existing conditions these people have? *

  1. Hiv Infection: 11 people, 68.75%
  2. Depression: 3 people, 18.75%
  3. Indigestion: 3 people, 18.75%
  4. Stress And Anxiety: 3 people, 18.75%
  5. Diabetes: 3 people, 18.75%
  6. High Blood Pressure: 3 people, 18.75%
  7. Hypersensitivity: 3 people, 18.75%
  8. Neuralgia (pain in one or more nerves): 3 people, 18.75%
  9. Tonsillitis (inflammation of tonsil): 2 people, 12.50%
  10. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Cimetidine and have Bone loss?

- Check whether Bone loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cimetidine:

Bone loss treatments and more:

How severe was Bone loss and when was it recovered:

Expand to all the drugs that have ingredients of cimetidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone loss:

Browse all the conditions that are associated with Bone loss:


How the study uses the data?

The study uses data from the FDA. It is based on cimetidine (the active ingredients of Cimetidine) and Cimetidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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