Cinnamon and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Cinnamon (cassia cinnamon), especially for people who are female, 60+ old, also take Vitamin D3, and have Restless leg syndrome.

The phase IV clinical study analyzes which people have Sciatica when taking Cinnamon. It is created by eHealthMe based on reports of 3,898 people who have side effects when taking Cinnamon from the FDA, and is updated regularly.

What is Cinnamon?

Cinnamon has active ingredients of cassia cinnamon. It is often used in diabetes. eHealthMe is studying from 4,109 Cinnamon users. Check the latest studies of Cinnamon.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,144 drugs and 1,422 conditions by eHealthMe. Check the latest studies of Sciatica.



On Nov, 16, 2025

3,898 people reported to have side effects when taking Cinnamon.
Among them, 16 people (0.41%) have Sciatica.

Could Cinnamon cause Sciatica?

Among these 16 people:

What is the gender of people who have Sciatica when taking Cinnamon? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Sciatica when taking Cinnamon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 37.5 %
  • 40-49: 0.0 %
  • 50-59: 25.0 %
  • 60+: 37.5 %

What are other drugs people take besides Cinnamon? *

  1. Vitamin D3: 9 people, 56.25%
  2. Cardizem: 4 people, 25.00%
  3. Zofran: 4 people, 25.00%
  4. Xanax: 4 people, 25.00%
  5. Humalog: 4 people, 25.00%
  6. Lantus: 4 people, 25.00%
  7. Valtrex: 4 people, 25.00%
  8. Crestor: 4 people, 25.00%
  9. Trelegy Ellipta: 4 people, 25.00%
  10. Escitalopram: 4 people, 25.00%

What are other side effects people have besides Sciatica? *

  1. Fall: 7 people, 43.75%
  2. Urinary Tract Infection: 6 people, 37.50%
  3. Pain: 5 people, 31.25%
  4. Nausea (feeling of having an urge to vomit): 5 people, 31.25%
  5. Fatigue (feeling of tiredness): 5 people, 31.25%
  6. Malaise (a feeling of general discomfort or uneasiness): 5 people, 31.25%
  7. Headache (pain in head): 4 people, 25.00%
  8. Cough: 4 people, 25.00%
  9. Herpes Zoster: 4 people, 25.00%
  10. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 25.00%

What are the existing conditions these people have? *

  1. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 18.75%
  2. The Flu (the flu is caused by an influenza virus): 2 people, 12.50%
  3. Balance Disorder: 2 people, 12.50%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 12.50%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 12.50%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  7. High Blood Cholesterol: 2 people, 12.50%
  8. Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 12.50%
  9. Type 2 Diabetes: 1 person, 6.25%
  10. High Blood Pressure: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Cinnamon and have Sciatica?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cinnamon:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of cassia cinnamon:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cinnamon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:

Drugs similar to Cinnamon and Sciatica :


How the study uses the data?

The study uses data from the FDA. It is based on cassia cinnamon (the active ingredients of Cinnamon) and Cinnamon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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