Cipro and Middle ear effusion - a phase IV clinical study of FDA data

Summary:

Middle ear effusion is reported as a side effect among people who take Cipro (ciprofloxacin hydrochloride), especially for people who are female, 40-49 old, also take Morphine, and have Crohn's disease.

The phase IV clinical study analyzes which people have Middle ear effusion when taking Cipro. It is created by eHealthMe based on reports of 32,835 people who have side effects when taking Cipro from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Middle ear effusion?

Middle ear effusion (fluid in middle ear) is found to be associated with 325 drugs and 447 conditions by eHealthMe. Check the latest studies of Middle ear effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

32,835 people reported to have side effects when taking Cipro.
Among them, 11 people (0.03%) have Middle ear effusion.

Among these 11 people:

What is the gender of people who have Middle ear effusion when taking Cipro? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Middle ear effusion when taking Cipro? *

What are other drugs people take besides Cipro? *

What are other side effects people have besides Middle ear effusion? *

Weakness: 7 people, 63.64%
Fatigue (feeling of tiredness): 5 people, 45.45%
Headache (pain in head): 5 people, 45.45%
Fever: 5 people, 45.45%
Otitis (ear infection): 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Loss Of Consciousness: 3 people, 27.27%
Drowsiness: 3 people, 27.27%
Hypoacusis (loss of hearing): 3 people, 27.27%
Ear Pain: 3 people, 27.27%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 27.27%
Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 2 people, 18.18%
Pain: 2 people, 18.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%
Fatigue (feeling of tiredness): 2 people, 18.18%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 2 people, 18.18%
Blood Potassium Decreased: 2 people, 18.18%
Bedwetting: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Cipro and have Middle ear effusion?

- Check whether Middle ear effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cipro:

Cipro (35,126 reports)

Browse all side effects of Cipro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Middle ear effusion:

Middle ear effusion (325 drugs)

Browse all the conditions that are associated with Middle ear effusion:

Middle ear effusion (447 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ciprofloxacin hydrochloride (the active ingredients of Cipro) and Cipro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.