Cipro and Pigmentation disorder - a phase IV clinical study of FDA data

Summary:

Pigmentation disorder is reported as a side effect among people who take Cipro (ciprofloxacin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Doxycycline, and have High blood pressure.

The phase IV clinical study analyzes which people have Pigmentation disorder when taking Cipro. It is created by eHealthMe based on reports of 32,835 people who have side effects when taking Cipro from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Pigmentation disorder?

Pigmentation disorder (disturbances of human skin colour) is found to be associated with 642 drugs and 772 conditions by eHealthMe. Check the latest studies of Pigmentation disorder.



On Jul, 13, 2026

32,835 people reported to have side effects when taking Cipro.
Among them, 31 people (0.09%) have Pigmentation disorder.

Could Cipro cause Pigmentation disorder?

Among these 31 people:

How long have people been on Cipro when they have Pigmentation disorder? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pigmentation disorder when taking Cipro? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Pigmentation disorder when taking Cipro? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 11.76 %
  • 40-49: 17.65 %
  • 50-59: 11.76 %
  • 60+: 52.94 %

What are other drugs people take besides Cipro? *

  1. Zometa: 19 people, 61.29%
  2. Levaquin: 19 people, 61.29%
  3. Hydrochlorothiazide: 19 people, 61.29%
  4. Folic Acid: 19 people, 61.29%
  5. Doxycycline: 19 people, 61.29%
  6. Lorazepam: 18 people, 58.06%
  7. Toprol-Xl: 17 people, 54.84%
  8. Fluconazole: 17 people, 54.84%
  9. Cloderm: 16 people, 51.61%
  10. Lupron: 16 people, 51.61%

What are other side effects people have besides Pigmentation disorder? *

  1. Renal Cyst (kidney cyst): 19 people, 61.29%
  2. Osteonecrosis Of Jaw (death of bone of jaw): 19 people, 61.29%
  3. Dyspnea (difficult or laboured breathing): 18 people, 58.06%
  4. Intervertebral Disc Protrusion (spinal disc protrusion): 17 people, 54.84%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 17 people, 54.84%
  6. Scoliosis (a medical condition in which a person's spine is curved from side to side): 17 people, 54.84%
  7. Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 17 people, 54.84%
  8. Mitral Valve Incompetence (inefficient heart valve): 17 people, 54.84%
  9. Swelling Face: 17 people, 54.84%
  10. Tendonitis (a condition that causes pain and swelling of tendons): 17 people, 54.84%

What are the existing conditions these people have? *

  1. High Blood Pressure: 15 people, 48.39%
  2. Metastasis (spreadable cancer to other organ from origin): 8 people, 25.81%
  3. Parkinson's Disease: 2 people, 6.45%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.45%
  5. Delusion (a false belief or opinion): 2 people, 6.45%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 6.45%
  7. Hallucinations (sensations that appear real but are created by your mind): 2 people, 6.45%
  8. Vulvovaginal Dryness: 1 person, 3.23%
  9. Hot Flush (sudden feelings of heat): 1 person, 3.23%
  10. Bipolar Disorder (mood disorder): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Cipro and have Pigmentation disorder?

- Check whether Pigmentation disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cipro:

Pigmentation disorder treatments and more:

How severe was Pigmentation disorder and when was it recovered:

Expand to all the drugs that have ingredients of ciprofloxacin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cipro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pigmentation disorder:

Browse all the conditions that are associated with Pigmentation disorder:


How the study uses the data?

The study uses data from the FDA. It is based on ciprofloxacin hydrochloride (the active ingredients of Cipro) and Cipro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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