Cisplatin and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Cisplatin (cisplatin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Taxol, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Cisplatin. It is created by eHealthMe based on reports of 92,672 people who have side effects when taking Cisplatin from the FDA, and is updated regularly.

What is Cisplatin?

Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 645 drugs and 807 conditions by eHealthMe. Check the latest studies of Hypernatraemia.



On Aug, 10, 2026

92,672 people reported to have side effects when taking Cisplatin.
Among them, 99 people (0.11%) have Hypernatraemia.

Could Cisplatin cause Hypernatraemia?

Among these 99 people:

How long have people been on Cisplatin when they have Hypernatraemia? *

  • < 1 month: 69.44 %
  • 1 - 6 months: 30.56 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypernatraemia when taking Cisplatin? *

  • female: 22.92 %
  • male: 77.08 %

What is the age of people who have Hypernatraemia when taking Cisplatin? *

  • 0-1: 0.0 %
  • 2-9: 3.85 %
  • 10-19: 1.28 %
  • 20-29: 2.56 %
  • 30-39: 2.56 %
  • 40-49: 6.41 %
  • 50-59: 19.23 %
  • 60+: 64.1 %

What are other drugs people take besides Cisplatin? *

  1. Paclitaxel: 7 people, 7.07%
  2. Taxol: 7 people, 7.07%
  3. Erbitux: 6 people, 6.06%
  4. Fluorouracil: 5 people, 5.05%
  5. Alimta: 5 people, 5.05%
  6. Proleukin: 4 people, 4.04%
  7. Metoclopramide: 4 people, 4.04%
  8. Coumadin: 4 people, 4.04%
  9. Dexamethasone: 4 people, 4.04%
  10. Biktarvy: 4 people, 4.04%

What are other side effects people have besides Hypernatraemia? *

  1. Dehydration (dryness resulting from the removal of water): 31 people, 31.31%
  2. Acute Kidney Failure: 22 people, 22.22%
  3. Weakness: 17 people, 17.17%
  4. Pneumonia: 16 people, 16.16%
  5. Fatigue (feeling of tiredness): 15 people, 15.15%
  6. Diarrhea: 15 people, 15.15%
  7. Thrombocytopenia (decrease of platelets in blood): 15 people, 15.15%
  8. Sepsis (a severe blood infection that can lead to organ failure and death): 13 people, 13.13%
  9. Fever: 13 people, 13.13%
  10. Confusional State: 13 people, 13.13%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 11 people, 11.11%
  2. Pain: 7 people, 7.07%
  3. Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 7 people, 7.07%
  4. Oesophageal Carcinoma (cancer tumour of oesophagus): 7 people, 7.07%
  5. High Blood Pressure: 6 people, 6.06%
  6. Oesophageal Adenocarcinoma (a cancer tumour of an epithelium in oesophagus): 5 people, 5.05%
  7. Hiv Infection: 4 people, 4.04%
  8. Tonsil Cancer: 4 people, 4.04%
  9. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 4 people, 4.04%
  10. Bone Sarcoma (bone cancer): 4 people, 4.04%

* Approximation only. Some reports may have incomplete information.

Do you take Cisplatin and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cisplatin:

Hypernatraemia treatments and more:

How severe was Hypernatraemia and when was it recovered:

Expand to all the drugs that have ingredients of cisplatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cisplatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Browse all the conditions that are associated with Hypernatraemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cisplatin (the active ingredients of Cisplatin) and Cisplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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