Cisplatin and Ovarian failure - a phase IV clinical study of FDA data
Summary:
Ovarian failure is reported as a side effect among people who take Cisplatin (cisplatin), especially for people who are 20-29 old, have been taking the drug for 1 - 6 months also take Methotrexate, and have Gestational trophoblastic tumor.
The phase IV clinical study analyzes which people have Ovarian failure when taking Cisplatin. It is created by eHealthMe based on reports of 92,672 people who have side effects when taking Cisplatin from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Ovarian failure?
Ovarian failure (ovary is not functioning) is found to be associated with 62 drugs and 157 conditions by eHealthMe. Check the latest studies of Ovarian failure.
92,672 people reported to have side effects when taking Cisplatin.
Among them, 16 people (0.02%) have Ovarian failure.

Among these 16 people:
How long have people been on Cisplatin when they have Ovarian failure? *
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the age of people who have Ovarian failure when taking Cisplatin? *
- 0-1: 0.0 %
- 2-9: 8.33 %
- 10-19: 16.67 %
- 20-29: 33.33 %
- 30-39: 16.67 %
- 40-49: 25.0 %
- 50-59: 0.0 %
- 60+: 0.0 %
What are other drugs people take besides Cisplatin? *
- Methotrexate: 6 people, 37.50%
- Etoposide: 4 people, 25.00%
- Dactinomycin: 3 people, 18.75%
- Ifosfamide: 2 people, 12.50%
- Adriamycin Pfs: 2 people, 12.50%
- Thiotepa: 1 person, 6.25%
- Cyclophosphamide: 1 person, 6.25%
- Carboplatin: 1 person, 6.25%
- Adriamycin Rdf: 1 person, 6.25%
What are other side effects people have besides Ovarian failure? *
- Amenorrhea (absence of a menstrual period in a woman of reproductive age): 6 people, 37.50%
- Vascular Injury: 2 people, 12.50%
- Hot Flush (sudden feelings of heat): 2 people, 12.50%
- Visual Impairment: 1 person, 6.25%
- Second Primary Malignancy (after getting cure a cancer, a new cancer development): 1 person, 6.25%
- Osteochondroma (a type of benign tumour that consists of cartilage and bone): 1 person, 6.25%
- Limb Asymmetry (consistent task discrepancy between the two lower limbs): 1 person, 6.25%
- Hepatic Steatosis (fatty liver disease): 1 person, 6.25%
- Hearing Loss: 1 person, 6.25%
- Haemangioma Of Liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver): 1 person, 6.25%
What are the existing conditions these people have? *
- Gestational Trophoblastic Tumor: 5 people, 31.25%
- Bone Sarcoma (bone cancer): 2 people, 12.50%
- Ovarian Epithelial Cancer (cancer that begins in the cells on the surface of the ovary): 1 person, 6.25%
- Ovarian Dysgerminoma Stage Unspecified (germ cell tumour of ovary): 1 person, 6.25%
- Breast Cancer Stage Ii: 1 person, 6.25%
- Breast Cancer Stage I: 1 person, 6.25%
- Breast Cancer: 1 person, 6.25%
- Bone Marrow Conditioning Regimen: 1 person, 6.25%
- Adrenal Neoplasm (abnormal growth of adrenal gland): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and have Ovarian failure?
- Check whether Ovarian failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Cisplatin:
- Cisplatin (92,837 reports)
Ovarian failure treatments and more:
- Ovarian failure (822 reports)
How severe was Ovarian failure and when was it recovered:
Expand to all the drugs that have ingredients of cisplatin:
Sub-studies by age:
0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Ovarian failure:
- Ovarian failure (62 drugs)
Browse all the conditions that are associated with Ovarian failure:
- Ovarian failure (157 conditions)
Related publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin (the active ingredients of Cisplatin) and Cisplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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