Claravis and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

Skin blushing/flushing is reported as a side effect among people who take Claravis (isotretinoin), especially for people who are male, 20-29 old, have been taking the drug for 1 - 6 months also take Niaspan, and have High density lipoprotein decreased.

The phase IV clinical study analyzes which people have Skin blushing/flushing when taking Claravis. It is created by eHealthMe based on reports of 9,471 people who have side effects when taking Claravis from the FDA, and is updated regularly.

What is Claravis?

Claravis has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,636 Claravis users. Check the latest studies of Claravis.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 2,010 drugs and 2,936 conditions by eHealthMe. Check the latest studies of Skin blushing/flushing.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

9,471 people reported to have side effects when taking Claravis.
Among them, 11 people (0.12%) have Skin blushing/flushing.

Could Claravis cause Skin blushing/flushing?

Among these 11 people:

How long have people been on Claravis when they have Skin blushing/flushing? *

What is the gender of people who have Skin blushing/flushing when taking Claravis? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Skin blushing/flushing when taking Claravis? *

What are other drugs people take besides Claravis? *

Niaspan: 3 people, 27.27%
Accutane: 2 people, 18.18%
Vitamin B12: 1 person, 9.09%
Tylenol: 1 person, 9.09%
Sotret: 1 person, 9.09%
Simvastatin: 1 person, 9.09%
Remicade: 1 person, 9.09%
Mobic: 1 person, 9.09%
Mavik: 1 person, 9.09%
Lisinopril And Hydrochlorothiazide: 1 person, 9.09%

What are other side effects people have besides Skin blushing/flushing? *

Abdominal Pain Upper: 3 people, 27.27%
Joint Pain: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Headache (pain in head): 3 people, 27.27%
Inflammatory Bowel Disease: 2 people, 18.18%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 18.18%
Fatigue (feeling of tiredness): 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%
Fainting (loss of consciousness and postural tone): 2 people, 18.18%
Irritable Bowel Syndrome: 2 people, 18.18%

What are the existing conditions these people have? *

High Density Lipoprotein Decreased: 2 people, 18.18%
High Blood Cholesterol: 1 person, 9.09%
Cyst (a closed sac): 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
Birth Control: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Claravis and have Skin blushing/flushing?

- Check whether Skin blushing/flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claravis:

Claravis (9,636 reports)

Browse all side effects of Claravis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,010 drugs)

Browse all the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,936 conditions)

Related publications that referenced our studies

Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Claravis) and Claravis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.