Claritin-d and Migraine - a phase IV clinical study of FDA data

Summary:

Migraine is reported as a side effect among people who take Claritin-d (loratadine; pseudoephedrine sulfate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Topamax, and have Narcolepsy.

The phase IV clinical study analyzes which people have Migraine when taking Claritin-d. It is created by eHealthMe based on reports of 6,243 people who have side effects when taking Claritin-d from the FDA, and is updated regularly.

What is Claritin-d?

Claritin-d has active ingredients of loratadine; pseudoephedrine sulfate. It is often used in allergies. eHealthMe is studying from 7,055 Claritin-d users. Check the latest studies of Claritin-d.

What is Migraine?

Migraine (headache) is found to be associated with 2,052 drugs and 2,349 conditions by eHealthMe. Check the latest studies of Migraine.

On Jul, 18, 2026

6,243 people reported to have side effects when taking Claritin-d.
Among them, 25 people (0.4%) have Migraine.

Among these 25 people:

How long have people been on Claritin-d when they have Migraine? *

What is the gender of people who have Migraine when taking Claritin-d? *

female: 78.26 %
male: 21.74 %

What is the age of people who have Migraine when taking Claritin-d? *

What are other drugs people take besides Claritin-d? *

What are other side effects people have besides Migraine? *

Pain: 7 people, 28.00%
Nausea (feeling of having an urge to vomit): 6 people, 24.00%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 24.00%
Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 5 people, 20.00%
Osteoporosis (bones weak and more likely to break): 4 people, 16.00%
Diarrhea: 4 people, 16.00%
Neck Crushing: 4 people, 16.00%
Spinal Pain (pain in spine): 4 people, 16.00%
Weakness: 4 people, 16.00%
Drug Ineffective: 3 people, 12.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 24.00%
Immunodeficiency Common Variable: 4 people, 16.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 16.00%
Seasonal Allergy (allergic condition due to certain season): 4 people, 16.00%
Osteoporosis (bones weak and more likely to break): 2 people, 8.00%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 8.00%
Back Pain: 2 people, 8.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 8.00%
Hypersensitivity: 2 people, 8.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin-d and have Migraine?

- Check whether Migraine is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin-d:

Claritin-d (7,055 reports)

Migraine treatments and more:

Migraine (234,063 reports)

How severe was Migraine and when was it recovered:

Migraine in Claritin-d

Expand to all the drugs that have ingredients of loratadine; pseudoephedrine sulfate:

Migraine and drugs with ingredients of loratadine; pseudoephedrine sulfate (30 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Claritin-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Migraine:

Migraine (2,052 drugs)

Browse all the conditions that are associated with Migraine:

Migraine (2,349 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine; pseudoephedrine sulfate (the active ingredients of Claritin-d) and Claritin-d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.