Claritin and Gallbladder operation - a phase IV clinical study of FDA data

Summary:

Gallbladder operation is reported as a side effect among people who take Claritin (loratadine), especially for people who are female, 50-59 old, also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Gallbladder operation when taking Claritin. It is created by eHealthMe based on reports of 74,516 people who have side effects when taking Claritin from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,317 Claritin users. Check the latest studies of Claritin.

What is Gallbladder operation?

Gallbladder operation is found to be associated with 340 drugs and 782 conditions by eHealthMe. Check the latest studies of Gallbladder operation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

74,516 people reported to have side effects when taking Claritin.
Among them, 14 people (0.02%) have Gallbladder operation.

Could Claritin cause Gallbladder operation?

Among these 14 people:

What is the gender of people who have Gallbladder operation when taking Claritin? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Gallbladder operation when taking Claritin? *

What are other drugs people take besides Claritin? *

What are other side effects people have besides Gallbladder operation? *

Arrhythmias (irregular heartbeat): 4 people, 28.57%
Mitral Valve Incompetence (inefficient heart valve): 3 people, 21.43%
High Blood Cholesterol: 2 people, 14.29%
Back Disorder: 2 people, 14.29%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 2 people, 14.29%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 14.29%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 2 people, 14.29%
Insomnia (sleeplessness): 2 people, 14.29%
Pulmonary Arterial Pressure Increased: 2 people, 14.29%
Dilatation Ventricular: 2 people, 14.29%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 7.14%
Multiple Allergies (allergy to multiple agents): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
Depression: 1 person, 7.14%
Cough: 1 person, 7.14%
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 1 person, 7.14%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Gallbladder operation?

- Check whether Gallbladder operation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin:

Claritin (77,317 reports)

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder operation:

Gallbladder operation (340 drugs)

Browse all the conditions that are associated with Gallbladder operation:

Gallbladder operation (782 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.