Clexane and Necrosis - a phase IV clinical study of FDA data

Summary:

Necrosis is reported as a side effect among people who take Clexane (enoxaparin sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Trental, and have Depression.

The phase IV clinical study analyzes which people have Necrosis when taking Clexane. It is created by eHealthMe based on reports of 14,633 people who have side effects when taking Clexane from the FDA, and is updated regularly.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

What is Necrosis?

Necrosis (the death of body tissue) is found to be associated with 748 drugs and 970 conditions by eHealthMe. Check the latest studies of Necrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

14,633 people reported to have side effects when taking Clexane.
Among them, 11 people (0.08%) have Necrosis.

Among these 11 people:

How long have people been on Clexane when they have Necrosis? *

What is the gender of people who have Necrosis when taking Clexane? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Necrosis when taking Clexane? *

What are other drugs people take besides Clexane? *

What are other side effects people have besides Necrosis? *

Speech Impairment (Adult) (inability to speak (adult)): 4 people, 36.36%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 36.36%
Abasia (inability to walk): 3 people, 27.27%
Gangrene (body tissue dies): 3 people, 27.27%
Femur Fracture: 3 people, 27.27%
Fall: 3 people, 27.27%
Faecal Incontinence (a lack of control over passing stool): 3 people, 27.27%
Consciousness - Decreased: 3 people, 27.27%
Cerebral Haemorrhage (bleeding within the brain): 3 people, 27.27%
Cerebral Artery Embolism (sudden blocking of an artery by a clot or foreign material): 3 people, 27.27%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 27.27%
Cerebral Artery Embolism (sudden blocking of an artery by a clot or foreign material): 3 people, 27.27%
Depression: 3 people, 27.27%
Breast Cancer: 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Vein Disorder: 1 person, 9.09%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 9.09%
Breast Cancer Metastatic: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%
Cardiac Failure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Clexane and have Necrosis?

- Check whether Necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clexane:

Clexane (14,679 reports)

Necrosis treatments and more:

Necrosis (8,274 reports)

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Necrosis:

Necrosis (748 drugs)

Browse all the conditions that are associated with Necrosis:

Necrosis (970 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium (the active ingredients of Clexane) and Clexane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.