Clonidine hydrochloride and Ankylosing spondylitis - a phase IV clinical study of FDA data

Summary:

Ankylosing spondylitis is reported as a side effect among people who take Clonidine hydrochloride (clonidine hydrochloride), especially for people who are female, 20-29 old, have been taking the drug for 1 - 2 years also take Prednisone, and have Cataplexy.

The phase IV clinical study analyzes which people have Ankylosing spondylitis when taking Clonidine hydrochloride. It is created by eHealthMe based on reports of 4,628 people who have side effects when taking Clonidine hydrochloride from the FDA, and is updated regularly.

What is Clonidine hydrochloride?

Clonidine hydrochloride has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,643 Clonidine hydrochloride users. Check the latest studies of Clonidine hydrochloride.

What is Ankylosing spondylitis?

Ankylosing spondylitis (type of arthritis affecting the spine) is found to be associated with 746 drugs and 1,048 conditions by eHealthMe. Check the latest studies of Ankylosing spondylitis.

On Jul, 19, 2026

4,628 people reported to have side effects when taking Clonidine hydrochloride.
Among them, 14 people (0.3%) have Ankylosing spondylitis.

Could Clonidine hydrochloride cause Ankylosing spondylitis?

Among these 14 people:

How long have people been on Clonidine hydrochloride when they have Ankylosing spondylitis? *

What is the gender of people who have Ankylosing spondylitis when taking Clonidine hydrochloride? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Ankylosing spondylitis when taking Clonidine hydrochloride? *

What are other drugs people take besides Clonidine hydrochloride? *

What are other side effects people have besides Ankylosing spondylitis? *

Weight Decreased: 11 people, 78.57%
Sinusitis (inflammation of sinus): 11 people, 78.57%
Nausea And Vomiting: 10 people, 71.43%
Indigestion: 10 people, 71.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 71.43%
Stress And Anxiety: 10 people, 71.43%
Sleep Disorder: 9 people, 64.29%
Nausea (feeling of having an urge to vomit): 9 people, 64.29%
Nasopharyngitis (inflammation of the nasopharynx): 9 people, 64.29%
Gait Disturbance: 9 people, 64.29%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Drowsiness: 4 people, 28.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 28.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 21.43%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 21.43%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
Nausea And Vomiting: 2 people, 14.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 14.29%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 7.14%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine hydrochloride and have Ankylosing spondylitis?

- Check whether Ankylosing spondylitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine hydrochloride:

Clonidine hydrochloride (5,643 reports)

Browse all side effects of Clonidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (746 drugs)

Browse all the conditions that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (1,048 conditions)

Related publications that referenced our studies

Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .
Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine hydrochloride (the active ingredients of Clonidine hydrochloride) and Clonidine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.