Clonidine and Blood pressure systolic decreased - a phase IV clinical study of FDA data

Summary:

Blood pressure systolic decreased is reported as a side effect among people who take Clonidine (clonidine), especially for people who are female, 40-49 old, also take Escitalopram, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Blood pressure systolic decreased when taking Clonidine. It is created by eHealthMe based on reports of 63,883 people who have side effects when taking Clonidine from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Blood pressure systolic decreased?

Blood pressure systolic decreased is found to be associated with 575 drugs and 645 conditions by eHealthMe. Check the latest studies of Blood pressure systolic decreased.

On Jul, 19, 2026

63,883 people reported to have side effects when taking Clonidine.
Among them, 49 people (0.08%) have Blood pressure systolic decreased.

Could Clonidine cause Blood pressure systolic decreased?

Among these 49 people:

What is the gender of people who have Blood pressure systolic decreased when taking Clonidine? *

female: 88.37 %
male: 11.63 %

What is the age of people who have Blood pressure systolic decreased when taking Clonidine? *

What are other drugs people take besides Clonidine? *

Escitalopram: 15 people, 30.61%
Lorazepam: 6 people, 12.24%
Atenolol: 5 people, 10.20%
Spironolactone: 3 people, 6.12%
Amlodipine: 3 people, 6.12%
Folic Acid: 3 people, 6.12%
Gabapentin: 3 people, 6.12%
Lipitor: 3 people, 6.12%
Propranolol Hydrochloride: 3 people, 6.12%
Zopiclone: 3 people, 6.12%

What are other side effects people have besides Blood pressure systolic decreased? *

Coma Scale Abnormal: 19 people, 38.78%
Overdose: 18 people, 36.73%
Heart Rate Decreased: 8 people, 16.33%
Blood Glucose Increased: 7 people, 14.29%
Weakness: 6 people, 12.24%
Oxygen Saturation Decreased: 6 people, 12.24%
Hypotension (abnormally low blood pressure): 6 people, 12.24%
Fainting (loss of consciousness and postural tone): 4 people, 8.16%
Celiac Disease - Sprue (a disease of the small intestine): 3 people, 6.12%
Dizziness: 3 people, 6.12%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.12%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 4.08%
Joint Stiffness: 2 people, 4.08%
Joint Pain: 2 people, 4.08%
Back Pain: 2 people, 4.08%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.08%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 1 person, 2.04%
Renal Cancer Stage Iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body): 1 person, 2.04%
Osteoporosis (bones weak and more likely to break): 1 person, 2.04%
Orthostatic Hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Blood pressure systolic decreased?

- Check whether Blood pressure systolic decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine:

Clonidine (65,644 reports)

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood pressure systolic decreased:

Blood pressure systolic decreased (575 drugs)

Browse all the conditions that are associated with Blood pressure systolic decreased:

Blood pressure systolic decreased (645 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.