Clonidine and Cholestasis - a phase IV clinical study of FDA data

Summary:

Cholestasis is reported as a side effect among people who take Clonidine (clonidine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Amlodipine, and have Pain.

The phase IV clinical study analyzes which people have Cholestasis when taking Clonidine. It is created by eHealthMe based on reports of 63,883 people who have side effects when taking Clonidine from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Cholestasis?

Cholestasis (a condition where bile cannot flow from the liver to the duodenum) is found to be associated with 1,034 drugs and 1,807 conditions by eHealthMe. Check the latest studies of Cholestasis.

On Jul, 07, 2026

63,883 people reported to have side effects when taking Clonidine.
Among them, 54 people (0.08%) have Cholestasis.

Among these 54 people:

How long have people been on Clonidine when they have Cholestasis? *

What is the gender of people who have Cholestasis when taking Clonidine? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Cholestasis when taking Clonidine? *

What are other drugs people take besides Clonidine? *

What are other side effects people have besides Cholestasis? *

Nausea (feeling of having an urge to vomit): 9 people, 16.67%
Nausea And Vomiting: 7 people, 12.96%
Gallstones (stone formation by bile component): 6 people, 11.11%
Hepatic Fibrosis (scarring process that represents the liver's response to injury): 6 people, 11.11%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 6 people, 11.11%
Pneumonia: 6 people, 11.11%
Cardiac Arrest: 5 people, 9.26%
Hepatitis (inflammation of the liver): 5 people, 9.26%
Diabetes Mellitus Inadequate Control: 5 people, 9.26%
Confusional State: 5 people, 9.26%

What are the existing conditions these people have? *

Pain: 11 people, 20.37%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 16.67%
Sleep Disorder: 8 people, 14.81%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 5.56%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 3.70%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 3.70%
Adenovirus Infection: 2 people, 3.70%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 3.70%
Erythema Multiforme (a type of hypersensitivity reaction): 2 people, 3.70%
Nausea (feeling of having an urge to vomit): 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Cholestasis?

- Check whether Cholestasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine:

Clonidine (65,644 reports)

Cholestasis treatments and more:

Cholestasis (23,731 reports)

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cholestasis:

Cholestasis (1,034 drugs)

Browse all the conditions that are associated with Cholestasis:

Cholestasis (1,807 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.