Clonidine and Muscle function loss - a phase IV clinical study of FDA data

Summary:

Muscle function loss is reported as a side effect among people who take Clonidine (clonidine), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Insulin, and have Pain.

The phase IV clinical study analyzes which people have Muscle function loss when taking Clonidine. It is created by eHealthMe based on reports of 63,883 people who have side effects when taking Clonidine from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Muscle function loss?

Muscle function loss is found to be associated with 1,001 drugs and 1,521 conditions by eHealthMe. Check the latest studies of Muscle function loss.

On Jul, 28, 2026

63,883 people reported to have side effects when taking Clonidine.
Among them, 91 people (0.14%) have Muscle function loss.

Could Clonidine cause Muscle function loss?

Among these 91 people:

How long have people been on Clonidine when they have Muscle function loss? *

What is the gender of people who have Muscle function loss when taking Clonidine? *

female: 40.74 %
male: 59.26 %

What is the age of people who have Muscle function loss when taking Clonidine? *

What are other drugs people take besides Clonidine? *

What are other side effects people have besides Muscle function loss? *

Arrhythmias (irregular heartbeat): 46 people, 50.55%
Pain In Extremity: 45 people, 49.45%
Weakness: 44 people, 48.35%
Pneumonia: 41 people, 45.05%
Hypoaesthesia (reduced sense of touch or sensation): 40 people, 43.96%
Hypotonia (low muscle tone): 38 people, 41.76%
Mobility Decreased (ability to move is reduced): 38 people, 41.76%
Sepsis (a severe blood infection that can lead to organ failure and death): 38 people, 41.76%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 37 people, 40.66%
Cardiopulmonary Failure (cessation of normal circulation of the blood due to failure of the heart to contract): 36 people, 39.56%

What are the existing conditions these people have? *

Pain: 10 people, 10.99%
Pain In Extremity: 4 people, 4.40%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 4 people, 4.40%
High Blood Cholesterol: 3 people, 3.30%
Heart Attack: 3 people, 3.30%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 3.30%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 3.30%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 3.30%
Spinal Pain (pain in spine): 3 people, 3.30%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.20%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Muscle function loss?

- Check whether Muscle function loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine:

Clonidine (65,644 reports)

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle function loss:

Muscle function loss (1,001 drugs)

Browse all the conditions that are associated with Muscle function loss:

Muscle function loss (1,521 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.