Clonidine and Spinal fusion surgery - a phase IV clinical study of FDA data

Summary:

Spinal fusion surgery is reported as a side effect among people who take Clonidine (clonidine), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Lyrica, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Spinal fusion surgery when taking Clonidine. It is created by eHealthMe based on reports of 63,883 people who have side effects when taking Clonidine from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Spinal fusion surgery?

Spinal fusion surgery is found to be associated with 493 drugs and 422 conditions by eHealthMe. Check the latest studies of Spinal fusion surgery.



On Aug, 08, 2026

63,883 people reported to have side effects when taking Clonidine.
Among them, 28 people (0.04%) have Spinal fusion surgery.

Could Clonidine cause Spinal fusion surgery?

Among these 28 people:

How long have people been on Clonidine when they have Spinal fusion surgery? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Spinal fusion surgery when taking Clonidine? *

  • female: 76.92 %
  • male: 23.08 %

What is the age of people who have Spinal fusion surgery when taking Clonidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.76 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.52 %
  • 50-59: 23.81 %
  • 60+: 61.9 %

What are other drugs people take besides Clonidine? *

  1. Lyrica: 12 people, 42.86%
  2. Lasix: 11 people, 39.29%
  3. Percocet: 9 people, 32.14%
  4. Prednisone: 9 people, 32.14%
  5. Folic Acid: 9 people, 32.14%
  6. Xanax: 9 people, 32.14%
  7. Methotrexate: 8 people, 28.57%
  8. Ultram: 8 people, 28.57%
  9. Lovaza: 8 people, 28.57%
  10. Flexeril: 8 people, 28.57%

What are other side effects people have besides Spinal fusion surgery? *

  1. Disability: 11 people, 39.29%
  2. Pain: 11 people, 39.29%
  3. Weakness: 10 people, 35.71%
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 9 people, 32.14%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 32.14%
  6. Irritable Bowel Syndrome: 9 people, 32.14%
  7. Injury: 9 people, 32.14%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 32.14%
  9. Anaemia (lack of blood): 8 people, 28.57%
  10. Hand Deformity: 8 people, 28.57%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 35.71%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 21.43%
  3. Pain: 3 people, 10.71%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 10.71%
  5. Hiv Infection: 2 people, 7.14%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 7.14%
  7. Back Pain: 2 people, 7.14%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.14%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 3.57%
  10. Asthma: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Spinal fusion surgery?

- Check whether Spinal fusion surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine:

Spinal fusion surgery treatments and more:

How severe was Spinal fusion surgery and when was it recovered:

Expand to all the drugs that have ingredients of clonidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal fusion surgery:

Browse all the conditions that are associated with Spinal fusion surgery:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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