Clopidogrel and Amputation - a phase IV clinical study of FDA data

Summary:

Amputation is reported as a side effect among people who take Clopidogrel (clopidogrel), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Heparin, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Amputation when taking Clopidogrel. It is created by eHealthMe based on reports of 91,038 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

What is Amputation?

Amputation is found to be associated with 145 drugs and 275 conditions by eHealthMe. Check the latest studies of Amputation.

On Jul, 05, 2026

91,038 people reported to have side effects when taking Clopidogrel.
Among them, 11 people (0.01%) have Amputation.

Among these 11 people:

How long have people been on Clopidogrel when they have Amputation? *

What is the gender of people who have Amputation when taking Clopidogrel? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Amputation when taking Clopidogrel? *

What are other drugs people take besides Clopidogrel? *

What are other side effects people have besides Amputation? *

Peripheral Ischaemia (impaired circulation to an extremity): 4 people, 36.36%
Pain In Extremity: 2 people, 18.18%
Haematoma (collection of blood outside the blood vessels): 2 people, 18.18%
Angioedema (rapid swelling of the dermis): 1 person, 9.09%
Bleeding Disorders: 1 person, 9.09%
Genital Candidiasis (candidiasis (fungus)infection of genital): 1 person, 9.09%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 9.09%
Gangrene (body tissue dies): 1 person, 9.09%
Fever: 1 person, 9.09%
Dyspnea (difficult or laboured breathing): 1 person, 9.09%

What are the existing conditions these people have? *

Type 2 Diabetes: 3 people, 27.27%
Adverse Event: 2 people, 18.18%
Hyperglycemia (high blood sugar): 2 people, 18.18%
Blockage Of Leg Arteries: 2 people, 18.18%
Stress And Anxiety: 2 people, 18.18%
Cardiac Disorder: 2 people, 18.18%
Dyslipidaemia (abnormal amount of lipids): 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 1 person, 9.09%
Arterial Occlusive Disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Clopidogrel and have Amputation?

- Check whether Amputation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopidogrel:

Clopidogrel (92,160 reports)

Amputation treatments and more:

Amputation (1,504 reports)

Browse all side effects of Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Amputation:

Amputation (145 drugs)

Browse all the conditions that are associated with Amputation:

Amputation (275 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.