Clopidogrel and Hepatomegaly - a phase IV clinical study of FDA data

Summary:

Hepatomegaly is reported as a side effect among people who take Clopidogrel (clopidogrel), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Plavix, and have Primary myelofibrosis.

The phase IV clinical study analyzes which people have Hepatomegaly when taking Clopidogrel. It is created by eHealthMe based on reports of 91,038 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

What is Hepatomegaly?

Hepatomegaly (abnormal enlargement of the liver) is found to be associated with 1,304 drugs and 1,925 conditions by eHealthMe. Check the latest studies of Hepatomegaly.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

91,038 people reported to have side effects when taking Clopidogrel.
Among them, 81 people (0.09%) have Hepatomegaly.

Among these 81 people:

How long have people been on Clopidogrel when they have Hepatomegaly? *

What is the gender of people who have Hepatomegaly when taking Clopidogrel? *

female: 58.73 %
male: 41.27 %

What is the age of people who have Hepatomegaly when taking Clopidogrel? *

What are other drugs people take besides Clopidogrel? *

What are other side effects people have besides Hepatomegaly? *

Nausea (feeling of having an urge to vomit): 35 people, 43.21%
Fatigue (feeling of tiredness): 31 people, 38.27%
Weakness: 27 people, 33.33%
Aspartate Aminotransferase Increased: 25 people, 30.86%
Dyspnea (difficult or laboured breathing): 23 people, 28.40%
Nausea And Vomiting: 19 people, 23.46%
Pain In Extremity: 19 people, 23.46%
Anaemia (lack of blood): 19 people, 23.46%
Splenomegaly (enlargement of spleen): 19 people, 23.46%
Alanine Aminotransferase Increased: 17 people, 20.99%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 15 people, 18.52%
Breast Cancer Metastatic: 11 people, 13.58%
High Blood Pressure: 7 people, 8.64%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 6.17%
Gastritis (inflammation of stomach): 3 people, 3.70%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 3.70%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 2.47%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 2.47%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 2 people, 2.47%
Diabetes: 2 people, 2.47%

* Approximation only. Some reports may have incomplete information.

Do you take Clopidogrel and have Hepatomegaly?

- Check whether Hepatomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopidogrel:

Clopidogrel (92,160 reports)

Hepatomegaly treatments and more:

Hepatomegaly (20,071 reports)

Browse all side effects of Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatomegaly:

Hepatomegaly (1,304 drugs)

Browse all the conditions that are associated with Hepatomegaly:

Hepatomegaly (1,925 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.