Clopra and Cardiac tamponade - a phase IV clinical study of FDA data

Summary:

Cardiac tamponade is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Nausea.

The phase IV clinical study analyzes which people have Cardiac tamponade when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Cardiac tamponade?

Cardiac tamponade (fluid accumulates in heart covering) is found to be associated with 526 drugs and 775 conditions by eHealthMe. Check the latest studies of Cardiac tamponade.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 59 people (0.07%) have Cardiac tamponade.

Among these 59 people:

How long have people been on Clopra when they have Cardiac tamponade? *

What is the gender of people who have Cardiac tamponade when taking Clopra? *

female: 53.45 %
male: 46.55 %

What is the age of people who have Cardiac tamponade when taking Clopra? *

What are other drugs people take besides Clopra? *

What are other side effects people have besides Cardiac tamponade? *

Hypotension (abnormally low blood pressure): 25 people, 42.37%
Pericardial Effusion (fluid around the heart): 23 people, 38.98%
Cardiac Arrest: 17 people, 28.81%
Concomitant Disease Aggravated (advanced due to some of accompanying): 9 people, 15.25%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 9 people, 15.25%
Fever: 9 people, 15.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 13.56%
Multi-Organ Failure (multisystem organ failure): 7 people, 11.86%
Myocardial Rupture (damage to heart muscle ,tearing of the walls of the ventricles or atria of the heart): 7 people, 11.86%
Pleural Effusion (water on the lungs): 7 people, 11.86%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 18 people, 30.51%
Infection: 14 people, 23.73%
Stress And Anxiety: 13 people, 22.03%
Hypotension (abnormally low blood pressure): 12 people, 20.34%
Herpes Virus Infection: 11 people, 18.64%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 11 people, 18.64%
Cardiac Failure: 11 people, 18.64%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 18.64%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 10.17%
Post Procedural Haemorrhage (post procedural bleeding): 6 people, 10.17%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Cardiac tamponade?

- Check whether Cardiac tamponade is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Clopra (81,430 reports)

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac tamponade:

Cardiac tamponade (526 drugs)

Browse all the conditions that are associated with Cardiac tamponade:

Cardiac tamponade (775 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.