Clopra and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Ondansetron, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 655 drugs and 805 conditions by eHealthMe. Check the latest studies of Hypernatraemia.

On Jul, 18, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 74 people (0.09%) have Hypernatraemia.

Among these 74 people:

How long have people been on Clopra when they have Hypernatraemia? *

What is the gender of people who have Hypernatraemia when taking Clopra? *

female: 71.01 %
male: 28.99 %

What is the age of people who have Hypernatraemia when taking Clopra? *

What are other drugs people take besides Clopra? *

What are other side effects people have besides Hypernatraemia? *

Nausea (feeling of having an urge to vomit): 33 people, 44.59%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 33 people, 44.59%
Fatigue (feeling of tiredness): 32 people, 43.24%
Malaise (a feeling of general discomfort or uneasiness): 30 people, 40.54%
Pain In Jaw: 27 people, 36.49%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 27 people, 36.49%
Hair Loss: 27 people, 36.49%
Onychalgia (nail biting): 26 people, 35.14%
Haematemesis (vomiting of blood): 26 people, 35.14%
Pneumonia: 13 people, 17.57%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 27 people, 36.49%
Bone Disorder: 26 people, 35.14%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 9 people, 12.16%
Nausea (feeling of having an urge to vomit): 9 people, 12.16%
High Blood Pressure: 7 people, 9.46%
Pain: 6 people, 8.11%
Sedation: 6 people, 8.11%
Constipation: 5 people, 6.76%
Cough: 5 people, 6.76%
Embolism Venous (embolus may pass into the arterial system): 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Clopra (81,430 reports)

Hypernatraemia treatments and more:

Hypernatraemia (6,339 reports)

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Hypernatraemia (655 drugs)

Browse all the conditions that are associated with Hypernatraemia:

Hypernatraemia (805 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.