Clopra and Salivary hypersecretion - a phase IV clinical study of FDA data

Summary:

Salivary hypersecretion is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 5 - 10 years also take Ondansetron, and have Schizophrenia.

The phase IV clinical study analyzes which people have Salivary hypersecretion when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Salivary hypersecretion?

Salivary hypersecretion (excess saliva secretion) is found to be associated with 779 drugs and 1,338 conditions by eHealthMe. Check the latest studies of Salivary hypersecretion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 61 people (0.08%) have Salivary hypersecretion.

Could Clopra cause Salivary hypersecretion?

Among these 61 people:

How long have people been on Clopra when they have Salivary hypersecretion? *

What is the gender of people who have Salivary hypersecretion when taking Clopra? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Salivary hypersecretion when taking Clopra? *

What are other drugs people take besides Clopra? *

What are other side effects people have besides Salivary hypersecretion? *

Nausea And Vomiting: 22 people, 36.07%
Weight Decreased: 20 people, 32.79%
The Flu (the flu is caused by an influenza virus): 18 people, 29.51%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 15 people, 24.59%
Nausea (feeling of having an urge to vomit): 15 people, 24.59%
Dyskinesia (abnormality or impairment of voluntary movement): 14 people, 22.95%
General Physical Health Deterioration (weak health status): 14 people, 22.95%
White Blood Cell Count Decreased: 13 people, 21.31%
Pain In Extremity: 13 people, 21.31%
Emotional Distress: 13 people, 21.31%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 19 people, 31.15%
Nausea (feeling of having an urge to vomit): 14 people, 22.95%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 8 people, 13.11%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 11.48%
Diarrhea: 7 people, 11.48%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.84%
Nausea And Vomiting: 6 people, 9.84%
Choledocholithiasis (stones in the common bile duct): 5 people, 8.20%
Osteoporosis (bones weak and more likely to break): 5 people, 8.20%
Pancreatic Carcinoma (pancreatic cancer): 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Salivary hypersecretion?

- Check whether Salivary hypersecretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Clopra (81,430 reports)

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Salivary hypersecretion:

Salivary hypersecretion (779 drugs)

Browse all the conditions that are associated with Salivary hypersecretion:

Salivary hypersecretion (1,338 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.