Clopra and Sinus arrhythmia - a phase IV clinical study of FDA data

Summary:

Sinus arrhythmia is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Acetaminophen, and have Nausea.

The phase IV clinical study analyzes which people have Sinus arrhythmia when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Sinus arrhythmia?

Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle) is found to be associated with 371 drugs and 418 conditions by eHealthMe. Check the latest studies of Sinus arrhythmia.

On Jun, 17, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 18 people (0.02%) have Sinus arrhythmia.

Among these 18 people:

How long have people been on Clopra when they have Sinus arrhythmia? *

What is the gender of people who have Sinus arrhythmia when taking Clopra? *

female: 72.22 %
male: 27.78 %

What is the age of people who have Sinus arrhythmia when taking Clopra? *

What are other drugs people take besides Clopra? *

Acetaminophen: 10 people, 55.56%
Cisplatin: 8 people, 44.44%
Ondansetron: 8 people, 44.44%
Aprepitant: 6 people, 33.33%
Diazepam: 6 people, 33.33%
Lactulose: 6 people, 33.33%
Ondansetron Hydrochloride: 4 people, 22.22%
Dexamethasone: 4 people, 22.22%
Dexamethasone Sodium Phosphate: 4 people, 22.22%
Reglan: 3 people, 16.67%

What are other side effects people have besides Sinus arrhythmia? *

Electrocardiogram T Wave Inversion: 9 people, 50.00%
Dyskinesia (abnormality or impairment of voluntary movement): 6 people, 33.33%
Nausea (feeling of having an urge to vomit): 5 people, 27.78%
Abdominal Pain: 5 people, 27.78%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 22.22%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 22.22%
Ventricular Extrasystoles (premature cardiac contraction): 4 people, 22.22%
Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 4 people, 22.22%
Nausea And Vomiting: 4 people, 22.22%
Gastric Ulcer (stomach ulcer): 3 people, 16.67%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 38.89%
Pain: 6 people, 33.33%
Nausea And Vomiting: 6 people, 33.33%
Constipation: 6 people, 33.33%
Sedation: 6 people, 33.33%
Osteosarcoma (a cancerous (malignant) bone tumour): 5 people, 27.78%
Bone Sarcoma (bone cancer): 4 people, 22.22%
Stress And Anxiety: 2 people, 11.11%
Gastric Ph Decreased: 2 people, 11.11%
Bacterial Infection: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Sinus arrhythmia?

- Check whether Sinus arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Clopra (81,430 reports)

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus arrhythmia:

Sinus arrhythmia (371 drugs)

Browse all the conditions that are associated with Sinus arrhythmia:

Sinus arrhythmia (418 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.