Clopra and Status epilepticus - a phase IV clinical study of FDA data

Summary:

Status epilepticus is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Midazolam, and have Seizures.

The phase IV clinical study analyzes which people have Status epilepticus when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Status epilepticus?

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure) is found to be associated with 662 drugs and 949 conditions by eHealthMe. Check the latest studies of Status epilepticus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 90 people (0.11%) have Status epilepticus.

Could Clopra cause Status epilepticus?

Among these 90 people:

How long have people been on Clopra when they have Status epilepticus? *

  • < 1 month: 82.35 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 5.88 %
  • 2 - 5 years: 11.76 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Status epilepticus when taking Clopra? *

  • female: 89.77 %
  • male: 10.23 %

What is the age of people who have Status epilepticus when taking Clopra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.1 %
  • 20-29: 7.32 %
  • 30-39: 46.34 %
  • 40-49: 4.88 %
  • 50-59: 3.66 %
  • 60+: 31.71 %

What are other drugs people take besides Clopra? *

  1. Midazolam: 30 people, 33.33%
  2. Ativan: 29 people, 32.22%
  3. Prednisone: 10 people, 11.11%
  4. Phenytoin: 9 people, 10.00%
  5. Propofol: 9 people, 10.00%
  6. Lorazepam: 9 people, 10.00%
  7. Levetiracetam: 8 people, 8.89%
  8. Acyclovir: 8 people, 8.89%
  9. Pyridoxine: 8 people, 8.89%
  10. Thiamine: 7 people, 7.78%

What are other side effects people have besides Status epilepticus? *

  1. Encephalopathy (functioning of the brain is affected by some agent or condition): 40 people, 44.44%
  2. Hypotension (abnormally low blood pressure): 40 people, 44.44%
  3. Drug Ineffective: 38 people, 42.22%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 37 people, 41.11%
  5. Loss Of Consciousness: 37 people, 41.11%
  6. Left Ventricular Dysfunction: 36 people, 40.00%
  7. Renal Impairment (severely reduced kidney function): 36 people, 40.00%
  8. Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 35 people, 38.89%
  9. Blood Bicarbonate Decreased: 34 people, 37.78%
  10. Renal Ischaemia (lack of blood supply to kidney): 33 people, 36.67%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 35 people, 38.89%
  2. Hypotension (abnormally low blood pressure): 34 people, 37.78%
  3. Bipolar Disorder (mood disorder): 34 people, 37.78%
  4. Pain: 11 people, 12.22%
  5. Hepatitis (inflammation of the liver): 7 people, 7.78%
  6. Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 7 people, 7.78%
  7. Depression: 5 people, 5.56%
  8. Multiple Myeloma (cancer of the plasma cells): 5 people, 5.56%
  9. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 5 people, 5.56%
  10. Local Anaesthesia: 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Status epilepticus?

- Check whether Status epilepticus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Status epilepticus treatments and more:

How severe was Status epilepticus and when was it recovered:

Expand to all the drugs that have ingredients of metoclopramide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Status epilepticus:

Browse all the conditions that are associated with Status epilepticus:


How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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