Clozapine and Multiple sclerosis aggravated - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis aggravated is reported as a side effect among people who take Clozapine (clozapine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Zopiclone, and have Depression.

The phase IV clinical study analyzes which people have Multiple sclerosis aggravated when taking Clozapine. It is created by eHealthMe based on reports of 83,401 people who have side effects when taking Clozapine from the FDA, and is updated regularly.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

What is Multiple sclerosis aggravated?

Multiple sclerosis aggravated (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,024 drugs and 323 conditions by eHealthMe. Check the latest studies of Multiple sclerosis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

83,401 people reported to have side effects when taking Clozapine.
Among them, 29 people (0.03%) have Multiple sclerosis aggravated.

Could Clozapine cause Multiple sclerosis aggravated?

Among these 29 people:

How long have people been on Clozapine when they have Multiple sclerosis aggravated? *

What is the gender of people who have Multiple sclerosis aggravated when taking Clozapine? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Multiple sclerosis aggravated when taking Clozapine? *

What are other drugs people take besides Clozapine? *

What are other side effects people have besides Multiple sclerosis aggravated? *

Weakness: 9 people, 31.03%
Fall: 7 people, 24.14%
Fatigue (feeling of tiredness): 7 people, 24.14%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 6 people, 20.69%
Dizziness: 6 people, 20.69%
Gait Disturbance: 5 people, 17.24%
Diarrhea: 5 people, 17.24%
Memory Loss: 4 people, 13.79%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 13.79%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 13.79%

What are the existing conditions these people have? *

Depression: 3 people, 10.34%
Bipolar Disorder (mood disorder): 2 people, 6.90%
Psychotic Disorder: 2 people, 6.90%
Constipation: 2 people, 6.90%
Urge Incontinence (urinary incontinence): 1 person, 3.45%
Indigestion: 1 person, 3.45%
Asthma: 1 person, 3.45%
Dizziness: 1 person, 3.45%
Emotional Disorder: 1 person, 3.45%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Clozapine and have Multiple sclerosis aggravated?

- Check whether Multiple sclerosis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozapine:

Clozapine (83,728 reports)

Browse all side effects of Clozapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (1,024 drugs)

Browse all the conditions that are associated with Multiple sclerosis aggravated:

Multiple sclerosis aggravated (323 conditions)

Related publications that referenced our studies

Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozapine) and Clozapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.