Clozapine and Toothaches - a phase IV clinical study of FDA data
Summary:
Toothaches is reported as a side effect among people who take Clozapine (clozapine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Ativan, and have Insomnia.
The phase IV clinical study analyzes which people have Toothaches when taking Clozapine. It is created by eHealthMe based on reports of 83,401 people who have side effects when taking Clozapine from the FDA, and is updated regularly.
What is Clozapine?
Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.
What is Toothaches?
Toothaches (tooth pain) is found to be associated with 1,328 drugs and 1,604 conditions by eHealthMe. Check the latest studies of Toothaches.
83,401 people reported to have side effects when taking Clozapine.
Among them, 17 people (0.02%) have Toothaches.

Among these 17 people:
How long have people been on Clozapine when they have Toothaches? *
- < 1 month: 80 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 20 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Toothaches when taking Clozapine? *
- female: 75 %
- male: 25 %
What is the age of people who have Toothaches when taking Clozapine? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 23.08 %
- 30-39: 7.69 %
- 40-49: 46.15 %
- 50-59: 15.38 %
- 60+: 7.69 %
What are other drugs people take besides Clozapine? *
- Fluoxetine: 4 people, 23.53%
- Thorazine: 4 people, 23.53%
- Ambien: 4 people, 23.53%
- Ativan: 4 people, 23.53%
- Latuda: 3 people, 17.65%
- Clozaril: 3 people, 17.65%
- Versacloz: 3 people, 17.65%
- Inderal: 2 people, 11.76%
- Invega: 2 people, 11.76%
- Klonopin: 2 people, 11.76%
What are other side effects people have besides Toothaches? *
- Heart Rate Increased: 6 people, 35.29%
- Psychotic Disorder: 6 people, 35.29%
- Weight Increased: 5 people, 29.41%
- Abnormal Behavior: 5 people, 29.41%
- Muscle Spasms (muscle contraction): 5 people, 29.41%
- Stress And Anxiety: 5 people, 29.41%
- Headache (pain in head): 4 people, 23.53%
- Fever: 4 people, 23.53%
- Fatigue (feeling of tiredness): 4 people, 23.53%
- Dyspnea (difficult or laboured breathing): 4 people, 23.53%
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 3 people, 17.65%
- Stress And Anxiety: 2 people, 11.76%
- Chest Pain: 2 people, 11.76%
- Constipation: 2 people, 11.76%
- Depression: 2 people, 11.76%
- Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 11.76%
- Hallucination, Auditory (perceiving sounds without auditory stimulus): 2 people, 11.76%
- High Blood Cholesterol: 2 people, 11.76%
- Sleep Disorder: 2 people, 11.76%
- Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Clozapine and have Toothaches?
- Check whether Toothaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Clozapine:
- Clozapine (83,728 reports)
Toothaches treatments and more:
- Toothaches (28,231 reports)
How severe was Toothaches and when was it recovered:
Expand to all the drugs that have ingredients of clozapine:
- Toothaches and drugs with ingredients of clozapine (123 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clozapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Toothaches:
- Toothaches (1,328 drugs)
Browse all the conditions that are associated with Toothaches:
- Toothaches (1,604 conditions)
Related publications that referenced our studies
- Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
- Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
- Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
- Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozapine) and Clozapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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