Codeine and Transaminases increased - a phase IV clinical study of FDA data

Summary:

Transaminases increased is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Morphine, and have Enterobacter infection.

The phase IV clinical study analyzes which people have Transaminases increased when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Transaminases increased?

Transaminases increased is found to be associated with 1,155 drugs and 1,514 conditions by eHealthMe. Check the latest studies of Transaminases increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

41,713 people reported to have side effects when taking Codeine.
Among them, 38 people (0.09%) have Transaminases increased.

Could Codeine cause Transaminases increased?

Among these 38 people:

How long have people been on Codeine when they have Transaminases increased? *

What is the gender of people who have Transaminases increased when taking Codeine? *

female: 61.76 %
male: 38.24 %

What is the age of people who have Transaminases increased when taking Codeine? *

What are other drugs people take besides Codeine? *

What are other side effects people have besides Transaminases increased? *

Hypoglycemia (low blood sugar): 12 people, 31.58%
Hypokalemia (low potassium): 12 people, 31.58%
Poisoning Deliberate: 11 people, 28.95%
Consciousness - Decreased: 9 people, 23.68%
Oedema Peripheral (superficial swelling): 8 people, 21.05%
Disturbance In Attention: 8 people, 21.05%
Cough: 8 people, 21.05%
Dyspnea (difficult or laboured breathing): 5 people, 13.16%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 13.16%
Enterobacter Infection (infection caused by bacteria of the family enterobacteriaceae): 4 people, 10.53%

What are the existing conditions these people have? *

Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 4 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.53%
Enterobacter Infection (infection caused by bacteria of the family enterobacteriaceae): 4 people, 10.53%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 7.89%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 5.26%
Oedema Peripheral (superficial swelling): 1 person, 2.63%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 2.63%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 2.63%
Headache (pain in head): 1 person, 2.63%
Cough: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Transaminases increased?

- Check whether Transaminases increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Codeine (42,342 reports)

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Transaminases increased:

Transaminases increased (1,155 drugs)

Browse all the conditions that are associated with Transaminases increased:

Transaminases increased (1,514 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.