Anzemet and Erbitux drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anzemet (dolasetron mesylate) and Erbitux (cetuximab). Common drug interactions include cardio-respiratory arrest among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Anzemet and Erbitux. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Anzemet?

Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.

What is Erbitux?

Erbitux has active ingredients of cetuximab. It is often used in cancer. eHealthMe is studying from 19,276 Erbitux users. Check the latest studies of Erbitux.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

50 people who take Anzemet and Erbitux together, and have interactions are studied.

Anzemet and Erbitux drug interactions.

What are the common drug interactions of Anzemet and Erbitux, by gender? *:

female:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Chest discomfort
  3. Chills (felling of cold)
  4. Colon cancer recurrent
  5. Conjunctivitis (pink eye)
  6. Decreased appetite
  7. Diplopia (double vision)
  8. Dysuria (painful or difficult urination)
  9. Eye redness
  10. Eyelid margin crusting (crusting at the lid margins, generally worse on waking)

male:

  1. Death
  2. Fatigue (feeling of tiredness)
  3. Anaphylactic reaction (serious allergic reaction)
  4. Cardiac disorder
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Eye pruritus (eye itching)
  7. Injection site discolouration
  8. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  9. Mucosal inflammation (infection of mucous membrane)
  10. Stomatitis (inflammation of mucous membrane of mouth)

What are the common drug interactions of Anzemet and Erbitux, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Acne (skin problems that cause pimples)
  2. Dry skin
  3. Hypoaesthesia (reduced sense of touch or sensation)

40-49:

  1. Hypotension (abnormally low blood pressure)
  2. Injection site discolouration
  3. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  4. Mucosal inflammation (infection of mucous membrane)
  5. Pyrexia (fever)
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Abdominal pain
  8. Body temperature increased
  9. Diplopia (double vision)
  10. Epistaxis (bleed from the nose)

50-59:

  1. Nephrolithiasis (calculi in the kidneys)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  4. Oedema peripheral (superficial swelling)
  5. Oxygen saturation decreased
  6. Palmar erythema (reddening of the palms at the thenar and hypothenar eminences)
  7. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  8. Pyrexia (fever)
  9. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  10. Rash papular (redness with papule)

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Abdominal pain
  5. Abdominal pain lower
  6. Anaemia (lack of blood)
  7. Arthralgia (joint pain)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Asthenia (weakness)
  10. Bone pain

What are the existing conditions these people have? *

  1. Colon Cancer: 14 people, 28.00%
  2. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 9 people, 18.00%
  3. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 7 people, 14.00%
  4. Oral Cancer (mouth cancer): 4 people, 8.00%
  5. Neoplasm Malignant (cancer tumour): 3 people, 6.00%
  6. Nausea (feeling of having an urge to vomit): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Anzemet and Erbitux?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Anzemet and Erbitux:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Anzemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Erbitux:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anzemet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Erbitux and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dolasetron mesylate and cetuximab (the active ingredients of Anzemet and Erbitux, respectively), and Anzemet and Erbitux (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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