Valsartan and Symproic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valsartan (valsartan) and Symproic (naldemedine tosylate). Common drug interactions include constipation among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Valsartan and Symproic. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Valsartan?

Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.

What is Symproic?

Symproic has active ingredients of naldemedine tosylate. eHealthMe is studying from 1,487 Symproic users. Check the latest studies of Symproic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

18 people who take Valsartan and Symproic together, and have interactions are studied.

Valsartan and Symproic drug interactions.

What are the common drug interactions of Valsartan and Symproic, by gender? *:

female:

Constipation
Pyrexia (fever)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Incontinence (lack of moderation or self-control)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Polyuria (production of too much dilute urine)
Thirst
Balance disorder
Breast cancer

male:

Pleural effusion (water on the lungs)
Cardiac tamponade (fluid accumulates in heart covering)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Constipation
Disease recurrence
Hypokalaemia (low potassium)
Insomnia (sleeplessness)
Vomiting
Coagulation factor deficiency (lack of clotting substance in blood)
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)

What are the common drug interactions of Valsartan and Symproic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Balance disorder
Fall

60+:

Constipation
Pyrexia (fever)
Cardiac tamponade (fluid accumulates in heart covering)
Coagulation factor deficiency (lack of clotting substance in blood)
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
Febrile neutropenia (fever with reduced white blood cells)
Granulocytopenia (lack of granulocyte)
Iron deficiency anaemia
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pericarditis malignant (cancerous inflammation of the pericardium)

What are the existing conditions these people have? *

Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 6 people, 33.33%
Cancer Pain: 4 people, 22.22%
Constipation: 4 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 2 people, 11.11%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 11.11%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 11.11%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 11.11%
Insomnia (sleeplessness): 2 people, 11.11%
Itching: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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