Coenzyme q10 and Major depression - a phase IV clinical study of FDA data

Summary:

Major depression is reported as a side effect among people who take Coenzyme q10 (coenzyme q - 10), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Major depression when taking Coenzyme q10. It is created by eHealthMe based on reports of 23,203 people who have side effects when taking Coenzyme q10 from the FDA, and is updated regularly.

What is Coenzyme q10?

Coenzyme q10 has active ingredients of coenzyme q - 10. It is often used in high blood cholesterol. eHealthMe is studying from 23,438 Coenzyme q10 users. Check the latest studies of Coenzyme q10.

What is Major depression?

Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 804 drugs and 1,475 conditions by eHealthMe. Check the latest studies of Major depression.

On Jul, 06, 2026

23,203 people reported to have side effects when taking Coenzyme q10.
Among them, 16 people (0.07%) have Major depression.

Could Coenzyme q10 cause Major depression?

Among these 16 people:

How long have people been on Coenzyme q10 when they have Major depression? *

What is the gender of people who have Major depression when taking Coenzyme q10? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Major depression when taking Coenzyme q10? *

What are other drugs people take besides Coenzyme q10? *

What are other side effects people have besides Major depression? *

Hypersensitivity: 6 people, 37.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 31.25%
Weight Increased: 4 people, 25.00%
Sluggishness (lacking alertness): 4 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Panic Disorder: 4 people, 25.00%
Drug Intolerance (drug sensitivity): 4 people, 25.00%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 4 people, 25.00%
Rashes (redness): 4 people, 25.00%
Stress And Anxiety: 4 people, 25.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 68.75%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 62.50%
Depression: 5 people, 31.25%
Osteoporosis (bones weak and more likely to break): 3 people, 18.75%
Sleep Disorder: 2 people, 12.50%
Cough: 2 people, 12.50%
Muscle Spasms (muscle contraction): 2 people, 12.50%
Drowsiness: 1 person, 6.25%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 6.25%
Curvature Of The Penis: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Coenzyme q10 and have Major depression?

- Check whether Major depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coenzyme q10:

Coenzyme q10 (23,438 reports)

Major depression treatments and more:

Major depression (44,979 reports)

Browse all side effects of Coenzyme q10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Major depression:

Major depression (804 drugs)

Browse all the conditions that are associated with Major depression:

Major depression (1,475 conditions)

Related publications that referenced our studies

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on coenzyme q - 10 (the active ingredients of Coenzyme q10) and Coenzyme q10 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.