Coenzyme q10 and Sjogren syndrome - a phase IV clinical study of FDA data

Summary:

Sjogren syndrome is reported as a side effect among people who take Coenzyme q10 (coenzyme q - 10), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Sjogren syndrome when taking Coenzyme q10. It is created by eHealthMe based on reports of 23,203 people who have side effects when taking Coenzyme q10 from the FDA, and is updated regularly.

What is Coenzyme q10?

Coenzyme q10 has active ingredients of coenzyme q - 10. It is often used in high blood cholesterol. eHealthMe is studying from 23,438 Coenzyme q10 users. Check the latest studies of Coenzyme q10.

What is Sjogren syndrome?

Sjogren syndrome (a disease that causes dryness in the mouth and eyes) is found to be associated with 616 drugs and 964 conditions by eHealthMe. Check the latest studies of Sjogren syndrome.

On Jul, 03, 2026

23,203 people reported to have side effects when taking Coenzyme q10.
Among them, 26 people (0.11%) have Sjogren syndrome.

Could Coenzyme q10 cause Sjogren syndrome?

Among these 26 people:

How long have people been on Coenzyme q10 when they have Sjogren syndrome? *

What is the gender of people who have Sjogren syndrome when taking Coenzyme q10? *

female: 96.15 %
male: 3.85 %

What is the age of people who have Sjogren syndrome when taking Coenzyme q10? *

What are other drugs people take besides Coenzyme q10? *

What are other side effects people have besides Sjogren syndrome? *

Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 8 people, 30.77%
Confusion: 7 people, 26.92%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 26.92%
Diarrhea: 7 people, 26.92%
Hypotension (abnormally low blood pressure): 6 people, 23.08%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 6 people, 23.08%
Insomnia (sleeplessness): 5 people, 19.23%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 15.38%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 11.54%
Migraine (headache): 3 people, 11.54%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 46.15%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 34.62%
Bipolar Disorder (mood disorder): 3 people, 11.54%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.69%
Insomnia (sleeplessness): 2 people, 7.69%
Drowsiness: 2 people, 7.69%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 1 person, 3.85%
Pain: 1 person, 3.85%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Coenzyme q10 and have Sjogren syndrome?

- Check whether Sjogren syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coenzyme q10:

Coenzyme q10 (23,438 reports)

Sjogren syndrome treatments and more:

Sjogren syndrome (12,488 reports)

Browse all side effects of Coenzyme q10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sjogren syndrome:

Sjogren syndrome (616 drugs)

Browse all the conditions that are associated with Sjogren syndrome:

Sjogren syndrome (964 conditions)

Related publications that referenced our studies

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on coenzyme q - 10 (the active ingredients of Coenzyme q10) and Coenzyme q10 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.