Cogentin and Bone density decreased - a phase IV clinical study of FDA data

Summary:

Bone density decreased is reported as a side effect among people who take Cogentin (benztropine mesylate), especially for people who are male, 40-49 old, also take Haldol, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bone density decreased when taking Cogentin. It is created by eHealthMe based on reports of 7,418 people who have side effects when taking Cogentin from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Bone density decreased?

Bone density decreased is found to be associated with 1,122 drugs and 948 conditions by eHealthMe. Check the latest studies of Bone density decreased.



On Aug, 05, 2026

7,418 people reported to have side effects when taking Cogentin.
Among them, 30 people (0.4%) have Bone density decreased.

Could Cogentin cause Bone density decreased?

Among these 30 people:

What is the gender of people who have Bone density decreased when taking Cogentin? *

  • female: 10 %
  • male: 90 %

What is the age of people who have Bone density decreased when taking Cogentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5 %
  • 40-49: 60 %
  • 50-59: 10 %
  • 60+: 25 %

What are other drugs people take besides Cogentin? *

  1. Haldol: 28 people, 93.33%
  2. Zometa: 27 people, 90.00%
  3. Aredia: 27 people, 90.00%
  4. Benztropine Mesylate: 27 people, 90.00%
  5. Sinemet: 27 people, 90.00%
  6. Flomax: 26 people, 86.67%
  7. Zoloft: 26 people, 86.67%
  8. Zyprexa: 26 people, 86.67%
  9. Toprol-Xl: 26 people, 86.67%
  10. Celebrex: 24 people, 80.00%

What are other side effects people have besides Bone density decreased? *

  1. Pain: 30 people, 100.00%
  2. Stress And Anxiety: 30 people, 100.00%
  3. Osteoporosis (bones weak and more likely to break): 28 people, 93.33%
  4. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 27 people, 90.00%
  5. Loose Tooth: 27 people, 90.00%
  6. Olfactory Nerve Disorder (disorders of taste and smell): 27 people, 90.00%
  7. Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 27 people, 90.00%
  8. Disturbance In Attention: 27 people, 90.00%
  9. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 27 people, 90.00%
  10. Muscle Strain (an injury to a muscle in which the muscle fibres tear): 27 people, 90.00%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 14 people, 46.67%
  2. Depression: 8 people, 26.67%
  3. Hiv Infection: 3 people, 10.00%
  4. Parkinson's Disease: 2 people, 6.67%
  5. Pain: 2 people, 6.67%
  6. High Blood Pressure: 2 people, 6.67%
  7. High Blood Cholesterol: 2 people, 6.67%
  8. Diabetes: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and have Bone density decreased?

- Check whether Bone density decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cogentin:

Bone density decreased treatments and more:

How severe was Bone density decreased and when was it recovered:

Expand to all the drugs that have ingredients of benztropine mesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cogentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone density decreased:

Browse all the conditions that are associated with Bone density decreased:


How the study uses the data?

The study uses data from the FDA. It is based on benztropine mesylate (the active ingredients of Cogentin) and Cogentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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