Colace and Application site hypersensitivity - a phase IV clinical study of FDA data

Summary:

Application site hypersensitivity is reported as a side effect among people who take Colace (docusate ), especially for people who are female, 60+ old, also take Sandostatin, and have Metastatic carcinoid tumor.

The phase IV clinical study analyzes which people have Application site hypersensitivity when taking Colace. It is created by eHealthMe based on reports of 41,100 people who have side effects when taking Colace from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Application site hypersensitivity?

Application site hypersensitivity is found to be associated with 101 drugs and 283 conditions by eHealthMe. Check the latest studies of Application site hypersensitivity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

41,100 people reported to have side effects when taking Colace.
Among them, 12 people (0.03%) have Application site hypersensitivity.

Could Colace cause Application site hypersensitivity?

Among these 12 people:

What is the gender of people who have Application site hypersensitivity when taking Colace? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Application site hypersensitivity when taking Colace? *

What are other drugs people take besides Colace? *

What are other side effects people have besides Application site hypersensitivity? *

Stress And Anxiety: 10 people, 83.33%
Injection Site Mass: 9 people, 75.00%
Itching: 9 people, 75.00%
Feeling Abnormal: 9 people, 75.00%
Fever: 9 people, 75.00%
Chills (felling of cold): 9 people, 75.00%
Hair Loss: 9 people, 75.00%
Burning Sensation: 9 people, 75.00%
Blood Pressure Systolic Increased: 9 people, 75.00%
Hot Flush (sudden feelings of heat): 9 people, 75.00%

What are the existing conditions these people have? *

Metastatic Carcinoid Tumor: 9 people, 75.00%
High Blood Pressure: 6 people, 50.00%
Gout (uric acid crystals building up in the body): 6 people, 50.00%
Back Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Colace and have Application site hypersensitivity?

- Check whether Application site hypersensitivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Colace:

Colace (41,841 reports)

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site hypersensitivity:

Application site hypersensitivity (101 drugs)

Browse all the conditions that are associated with Application site hypersensitivity:

Application site hypersensitivity (283 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on docusate (the active ingredients of Colace) and Colace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.