Combivir and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Combivir (lamivudine; zidovudine), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Bactrim, and have Trigeminal neuralgia.

The phase IV clinical study analyzes which people have Glaucoma when taking Combivir. It is created by eHealthMe based on reports of 15,371 people who have side effects when taking Combivir from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,235 drugs and 1,656 conditions by eHealthMe. Check the latest studies of Glaucoma.



On Jul, 19, 2026

15,371 people reported to have side effects when taking Combivir.
Among them, 25 people (0.16%) have Glaucoma.

Could Combivir cause Glaucoma?

Among these 25 people:

How long have people been on Combivir when they have Glaucoma? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 30 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 30 %
  • 5 - 10 years: 20 %
  • 10+ years: 0.0 %

What is the gender of people who have Glaucoma when taking Combivir? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Glaucoma when taking Combivir? *

  • 0-1: 20 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 50 %
  • 50-59: 10 %
  • 60+: 0.0 %

What are other drugs people take besides Combivir? *

  1. Retrovir: 9 people, 36.00%
  2. Bactrim: 9 people, 36.00%
  3. Neurontin: 8 people, 32.00%
  4. Norvir: 8 people, 32.00%
  5. Viracept: 7 people, 28.00%
  6. Sustiva: 6 people, 24.00%
  7. Truvada: 6 people, 24.00%
  8. Zerit: 6 people, 24.00%
  9. Ziagen: 6 people, 24.00%
  10. Viread: 5 people, 20.00%

What are other side effects people have besides Glaucoma? *

  1. Depression: 6 people, 24.00%
  2. Tooth Abscess (pus formation in tooth): 6 people, 24.00%
  3. Kidney Stones: 5 people, 20.00%
  4. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 5 people, 20.00%
  5. Blood Lactic Acid Increased: 5 people, 20.00%
  6. Blood Pyruvic Acid Decreased: 5 people, 20.00%
  7. Visual Acuity Reduced (reduced clearness of vision): 4 people, 16.00%
  8. Blood Amylase Increased: 4 people, 16.00%
  9. Optic Neuritis Retrobulbar (a form of optic neuritis in which the optic nerve, which is at the back of the eye, becomes inflamed): 4 people, 16.00%
  10. Mononeuritis Multiplex (a form of damage to one or more peripheral nerves): 4 people, 16.00%

What are the existing conditions these people have? *

  1. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 5 people, 20.00%
  2. Multiple Myeloma (cancer of the plasma cells): 3 people, 12.00%
  3. Pneumonia: 2 people, 8.00%
  4. High Blood Pressure: 2 people, 8.00%
  5. Dizziness: 2 people, 8.00%
  6. Allergic Rhinitis: 2 people, 8.00%
  7. Infection: 1 person, 4.00%
  8. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivir:

Glaucoma treatments and more:

How severe was Glaucoma and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine; zidovudine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Browse all the conditions that are associated with Glaucoma:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine (the active ingredients of Combivir) and Combivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: