Compazine and Hypomagnesaemia - a phase IV clinical study of FDA data

Summary:

Hypomagnesaemia is reported as a side effect among people who take Compazine (prochlorperazine maleate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Zofran, and have Pain.

The phase IV clinical study analyzes which people have Hypomagnesaemia when taking Compazine. It is created by eHealthMe based on reports of 13,599 people who have side effects when taking Compazine from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Hypomagnesaemia?

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood) is found to be associated with 1,030 drugs and 1,053 conditions by eHealthMe. Check the latest studies of Hypomagnesaemia.



On Jul, 15, 2026

13,599 people reported to have side effects when taking Compazine.
Among them, 59 people (0.43%) have Hypomagnesaemia.

Could Compazine cause Hypomagnesaemia?

Among these 59 people:

How long have people been on Compazine when they have Hypomagnesaemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypomagnesaemia when taking Compazine? *

  • female: 70 %
  • male: 30 %

What is the age of people who have Hypomagnesaemia when taking Compazine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.38 %
  • 20-29: 0.0 %
  • 30-39: 2.38 %
  • 40-49: 7.14 %
  • 50-59: 9.52 %
  • 60+: 78.57 %

What are other drugs people take besides Compazine? *

  1. Zofran: 33 people, 55.93%
  2. Tylenol: 17 people, 28.81%
  3. Decadron: 17 people, 28.81%
  4. Vitamin D3: 15 people, 25.42%
  5. Levaquin: 12 people, 20.34%
  6. Colace: 12 people, 20.34%
  7. Ativan: 12 people, 20.34%
  8. Vitamin E: 11 people, 18.64%
  9. Emla: 11 people, 18.64%
  10. Norco: 11 people, 18.64%

What are other side effects people have besides Hypomagnesaemia? *

  1. Hypokalemia (low potassium): 32 people, 54.24%
  2. Fatigue (feeling of tiredness): 30 people, 50.85%
  3. Thrombocytopenia (decrease of platelets in blood): 29 people, 49.15%
  4. Anaemia (lack of blood): 29 people, 49.15%
  5. Diarrhea: 22 people, 37.29%
  6. High Blood Pressure: 19 people, 32.20%
  7. Weight Decreased: 16 people, 27.12%
  8. Headache (pain in head): 16 people, 27.12%
  9. Constipation: 15 people, 25.42%
  10. Weakness: 15 people, 25.42%

What are the existing conditions these people have? *

  1. Pain: 28 people, 47.46%
  2. Constipation: 14 people, 23.73%
  3. Ovarian Cancer (cancer of ovary): 13 people, 22.03%
  4. Multiple Myeloma (cancer of the plasma cells): 7 people, 11.86%
  5. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 11.86%
  6. Fever: 6 people, 10.17%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 10.17%
  8. Blood Culture Positive: 5 people, 8.47%
  9. Stress And Anxiety: 3 people, 5.08%
  10. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and have Hypomagnesaemia?

- Check whether Hypomagnesaemia is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compazine:

Hypomagnesaemia treatments and more:

How severe was Hypomagnesaemia and when was it recovered:

Expand to all the drugs that have ingredients of prochlorperazine maleate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypomagnesaemia:

Browse all the conditions that are associated with Hypomagnesaemia:


How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine maleate (the active ingredients of Compazine) and Compazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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