Compazine and Ventricular tachycardia - a phase IV clinical study of FDA data

Summary:

Ventricular tachycardia is reported as a side effect among people who take Compazine (prochlorperazine maleate), especially for people who are male, 60+ old, also take Zofran, and have High blood pressure.

The phase IV clinical study analyzes which people have Ventricular tachycardia when taking Compazine. It is created by eHealthMe based on reports of 13,599 people who have side effects when taking Compazine from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Ventricular tachycardia?

Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart) is found to be associated with 1,292 drugs and 2,094 conditions by eHealthMe. Check the latest studies of Ventricular tachycardia.

On Jul, 04, 2026

13,599 people reported to have side effects when taking Compazine.
Among them, 20 people (0.15%) have Ventricular tachycardia.

Could Compazine cause Ventricular tachycardia?

Among these 20 people:

What is the gender of people who have Ventricular tachycardia when taking Compazine? *

female: 47.37 %
male: 52.63 %

What is the age of people who have Ventricular tachycardia when taking Compazine? *

What are other drugs people take besides Compazine? *

What are other side effects people have besides Ventricular tachycardia? *

Chest Pain: 11 people, 55.00%
Fatigue (feeling of tiredness): 10 people, 50.00%
Stress And Anxiety: 9 people, 45.00%
Pain: 8 people, 40.00%
Osteonecrosis Of Jaw (death of bone of jaw): 8 people, 40.00%
Thrombocytopenia (decrease of platelets in blood): 8 people, 40.00%
Pneumonia: 7 people, 35.00%
Dyspnea (difficult or laboured breathing): 7 people, 35.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 35.00%
Bone Disorder: 7 people, 35.00%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 40.00%
Multiple Myeloma (cancer of the plasma cells): 5 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 20.00%
Insomnia (sleeplessness): 3 people, 15.00%
High Blood Cholesterol: 3 people, 15.00%
Metastases To Bone (cancer spreads to bone): 3 people, 15.00%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 10.00%
Pain: 2 people, 10.00%
Breast Cancer Metastatic: 2 people, 10.00%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and have Ventricular tachycardia?

- Check whether Ventricular tachycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compazine:

Compazine (13,646 reports)

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular tachycardia:

Ventricular tachycardia (1,292 drugs)

Browse all the conditions that are associated with Ventricular tachycardia:

Ventricular tachycardia (2,094 conditions)

Related publications that referenced our studies

Amit K J Mandal, Umar F Khan, Constantinos G Missouris, "Ventricular tachycardia in a patient with sigmoid volvulus on treatment with donepezil", Clinical Toxicology, 2019 Jan .
Amit K J Mandal, Umar F Khan, Constantinos G Missouris, "Ventricular tachycardia in a patient with sigmoid volvulus on treatment with donepezil", Clinical Toxicology, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine maleate (the active ingredients of Compazine) and Compazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.