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Concerta and Impaired work ability - a phase IV clinical study of FDA data

Summary:

Impaired work ability is reported as a side effect among people who take Concerta (methylphenidate hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Crohn's disease.

The phase IV clinical study analyzes which people have Impaired work ability when taking Concerta. It is created by eHealthMe based on reports of 20,995 people who have side effects when taking Concerta from the FDA, and is updated regularly.

What is Concerta?

Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,040 Concerta users. Check the latest studies of Concerta.

What is Impaired work ability?

Impaired work ability is found to be associated with 1,012 drugs and 1,137 conditions by eHealthMe. Check the latest studies of Impaired work ability.

On Jul, 27, 2026

20,995 people reported to have side effects when taking Concerta.
Among them, 41 people (0.2%) have Impaired work ability.

Could Concerta cause Impaired work ability?

Among these 41 people:

How long have people been on Concerta when they have Impaired work ability? *

  • < 1 month: 37.5 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 12.5 %
  • 10+ years: 0.0 %

What is the gender of people who have Impaired work ability when taking Concerta? *

  • female: 59.46 %
  • male: 40.54 %

What is the age of people who have Impaired work ability when taking Concerta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 14.29 %
  • 20-29: 21.43 %
  • 30-39: 14.29 %
  • 40-49: 21.43 %
  • 50-59: 21.43 %
  • 60+: 7.14 %

What are other drugs people take besides Concerta? *

  1. Cymbalta: 4 people, 9.76%
  2. Methotrexate: 3 people, 7.32%
  3. Inflectra: 3 people, 7.32%
  4. Prednisone: 3 people, 7.32%
  5. Folic Acid: 3 people, 7.32%
  6. Imodium: 3 people, 7.32%
  7. Imuran: 3 people, 7.32%
  8. Aleve: 3 people, 7.32%
  9. Wellbutrin: 3 people, 7.32%
  10. Colestid: 3 people, 7.32%

What are other side effects people have besides Impaired work ability? *

  1. Disturbance In Attention: 7 people, 17.07%
  2. Drug Ineffective: 6 people, 14.63%
  3. Fatigue (feeling of tiredness): 6 people, 14.63%
  4. Memory Loss: 6 people, 14.63%
  5. High Blood Pressure: 5 people, 12.20%
  6. Drowsiness: 4 people, 9.76%
  7. Anger: 3 people, 7.32%
  8. Chest Pain: 3 people, 7.32%
  9. Intestinal Stenosis (partial obstruction that causes the centre opening of the intestine to become narrower): 3 people, 7.32%
  10. Constipation: 3 people, 7.32%

What are the existing conditions these people have? *

  1. Sleep Disorder: 3 people, 7.32%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.32%
  3. Birth Control: 2 people, 4.88%
  4. Oral Herpes (viral infection of mouth): 2 people, 4.88%
  5. Disturbance In Attention: 2 people, 4.88%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 4.88%
  7. Weakness: 1 person, 2.44%
  8. High Blood Pressure: 1 person, 2.44%
  9. Drowsiness: 1 person, 2.44%
  10. Eye Allergy: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Concerta and have Impaired work ability?

- Check whether Impaired work ability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Concerta:

Impaired work ability treatments and more:

How severe was Impaired work ability and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Concerta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired work ability:

Browse all the conditions that are associated with Impaired work ability:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Concerta) and Concerta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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