Contac 12 hour and Nausea aggravated - a phase IV clinical study of FDA data

Summary:

Nausea aggravated is reported as a side effect among people who take Contac 12 hour (chlorpheniramine maleate; phenylpropanolamine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Dimetapp, and have Nasopharyngitis.

The phase IV clinical study analyzes which people have Nausea aggravated when taking Contac 12 hour. It is created by eHealthMe based on reports of 1,131 people who have side effects when taking Contac 12 hour from the FDA, and is updated regularly.

What is Contac 12 hour?

Contac 12 hour has active ingredients of chlorpheniramine maleate; phenylpropanolamine hydrochloride. eHealthMe is studying from 1,137 Contac 12 hour users. Check the latest studies of Contac 12 hour.

What is Nausea aggravated?

Nausea aggravated (an urge to vomit) is found to be associated with 3,388 drugs and 1,082 conditions by eHealthMe. Check the latest studies of Nausea aggravated.

On Jul, 15, 2026

1,131 people reported to have side effects when taking Contac 12 hour.
Among them, 38 people (3.36%) have Nausea aggravated.

Could Contac 12 hour cause Nausea aggravated?

Among these 38 people:

How long have people been on Contac 12 hour when they have Nausea aggravated? *

What is the gender of people who have Nausea aggravated when taking Contac 12 hour? *

female: 71.05 %
male: 28.95 %

What is the age of people who have Nausea aggravated when taking Contac 12 hour? *

What are other drugs people take besides Contac 12 hour? *

Dimetapp: 13 people, 34.21%
Ibuprofen: 4 people, 10.53%
Vicks Formula 44: 2 people, 5.26%
Contac: 2 people, 5.26%
Enalapril Maleate: 2 people, 5.26%
Hydroxyzine: 2 people, 5.26%
Nifedipine: 2 people, 5.26%
Lortab: 1 person, 2.63%
Librax: 1 person, 2.63%
Metformin Hydrochloride: 1 person, 2.63%

What are other side effects people have besides Nausea aggravated? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 18 people, 47.37%
Injury: 14 people, 36.84%
Memory Loss: 12 people, 31.58%
Dizziness: 12 people, 31.58%
Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 9 people, 23.68%
Headache (pain in head): 9 people, 23.68%
Chest Pain: 8 people, 21.05%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 7 people, 18.42%
Fatigue (feeling of tiredness): 7 people, 18.42%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 7 people, 18.42%

What are the existing conditions these people have? *

Nasopharyngitis (inflammation of the nasopharynx): 14 people, 36.84%
Weight Decreased: 1 person, 2.63%
Sinus Pain: 1 person, 2.63%
Influenza Like Illness: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Contac 12 hour and have Nausea aggravated?

- Check whether Nausea aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Contac 12 hour:

Contac 12 hour (1,137 reports)

Nausea aggravated treatments and more:

Nausea aggravated (214 reports)

How severe was Nausea aggravated and when was it recovered:

Nausea aggravated in Contac 12 hour

Expand to all the drugs that have ingredients of chlorpheniramine maleate; phenylpropanolamine hydrochloride:

Nausea aggravated and drugs with ingredients of chlorpheniramine maleate; phenylpropanolamine hydrochloride (894 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Contac 12 hour:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea aggravated:

Nausea aggravated (3,388 drugs)

Browse all the conditions that are associated with Nausea aggravated:

Nausea aggravated (1,082 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorpheniramine maleate; phenylpropanolamine hydrochloride (the active ingredients of Contac 12 hour) and Contac 12 hour (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.