Coreg and Feeling cold - a phase IV clinical study of FDA data
Summary:
Feeling cold is reported as a side effect among people who take Coreg (carvedilol), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have Cardiac failure congestive.
The phase IV clinical study analyzes which people have Feeling cold when taking Coreg. It is created by eHealthMe based on reports of 48,155 people who have side effects when taking Coreg from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,577 Coreg users. Check the latest studies of Coreg.
What is Feeling cold?
Feeling cold is found to be associated with 1,390 drugs and 1,607 conditions by eHealthMe. Check the latest studies of Feeling cold.
48,155 people reported to have side effects when taking Coreg.
Among them, 129 people (0.27%) have Feeling cold.

Among these 129 people:
How long have people been on Coreg when they have Feeling cold? *
- < 1 month: 0.0 %
- 1 - 6 months: 16.67 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 50.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Feeling cold when taking Coreg? *
- female: 64.52 %
- male: 35.48 %
What is the age of people who have Feeling cold when taking Coreg? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 1 %
- 20-29: 1 %
- 30-39: 0.0 %
- 40-49: 9 %
- 50-59: 11 %
- 60+: 78 %
What are other drugs people take besides Coreg? *
- Lasix: 43 people, 33.33%
- Aspirin: 28 people, 21.71%
- Prilosec: 20 people, 15.50%
- Coumadin: 20 people, 15.50%
- Plavix: 20 people, 15.50%
- Digoxin: 19 people, 14.73%
- Synthroid: 18 people, 13.95%
- Lipitor: 17 people, 13.18%
- Lisinopril: 16 people, 12.40%
- Protonix: 15 people, 11.63%
What are other side effects people have besides Feeling cold? *
- Fatigue (feeling of tiredness): 43 people, 33.33%
- Weakness: 41 people, 31.78%
- Nausea (feeling of having an urge to vomit): 39 people, 30.23%
- Dizziness: 38 people, 29.46%
- Hypotension (abnormally low blood pressure): 34 people, 26.36%
- Dyspnea (difficult or laboured breathing): 33 people, 25.58%
- Diarrhea: 28 people, 21.71%
- Malaise (a feeling of general discomfort or uneasiness): 27 people, 20.93%
- Chest Pain: 26 people, 20.16%
- Urinary Tract Infection: 24 people, 18.60%
What are the existing conditions these people have? *
- Cardiac Failure Congestive: 13 people, 10.08%
- Pain: 10 people, 7.75%
- High Blood Cholesterol: 10 people, 7.75%
- Blood Pressure Abnormal: 8 people, 6.20%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 6.20%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 6.20%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 5.43%
- Osteoporosis (bones weak and more likely to break): 7 people, 5.43%
- Diabetes: 6 people, 4.65%
- Cardiac Disorder: 6 people, 4.65%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and have Feeling cold?
- Check whether Feeling cold is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Coreg:
- Coreg (49,577 reports)
Feeling cold treatments and more:
- Feeling cold (33,882 reports)
How severe was Feeling cold and when was it recovered:
Expand to all the drugs that have ingredients of carvedilol:
- Feeling cold and drugs with ingredients of carvedilol (364 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Coreg side effects:
- Coreg side effect: Fatigue (feeling of tiredness) (4,067 reports)
- Coreg side effect: Cardiac failure congestive (3,897 reports)
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Feeling cold:
- Prednisone side effect: Feeling cold (1,699 reports)
- Aspirin side effect: Feeling cold (1,596 reports)
- Metformin side effect: Feeling cold (1,124 reports)
- Methotrexate side effect: Feeling cold (1,074 reports)
- Humira side effect: Feeling cold (1,018 reports)
- Omeprazole side effect: Feeling cold (989 reports)
- Synthroid side effect: Feeling cold (988 reports)
- Vitamin d side effect: Feeling cold (979 reports)
- Avonex side effect: Feeling cold (938 reports)
- Amlodipine side effect: Feeling cold (917 reports)
Browse all the drugs that are associated with Feeling cold:
- Feeling cold (1,390 drugs)
Common conditions associated with Feeling cold:
- Ms: 3,096 reports
- Arthritis - rheumatoid: 1,676 reports
- Hypertension: 1,495 reports
- Hbp: 1,485 reports
- Pain: 1,329 reports
- Alternative medicine - pain relief: 1,308 reports
- High blood cholesterol: 888 reports
- Depression: 870 reports
- Osteoporosis: 756 reports
- Type 2 diabetes mellitus: 746 reports
Browse all the conditions that are associated with Feeling cold:
- Feeling cold (1,607 conditions)
Drugs similar to Coreg and Feeling cold :
- Accupril side effect: Feeling cold
- Adalat side effect: Feeling cold
- Altace side effect: Feeling cold
- Amlodipine side effect: Feeling cold
- Amlodipine besylate side effect: Feeling cold
- Amlodipine maleate; benazepril hydrochloride side effect: Feeling cold
- Aspirin side effect: Feeling cold
- Atacand side effect: Feeling cold
- Atenolol side effect: Feeling cold
- Atenolol and chlorthalidone side effect: Feeling cold
- Avalide side effect: Feeling cold
- Avapro side effect: Feeling cold
- Azor side effect: Feeling cold
- Benazepril hydrochloride side effect: Feeling cold
- Benicar side effect: Feeling cold
- Benicar hct side effect: Feeling cold
- Bisoprolol fumarate side effect: Feeling cold
- Bystolic side effect: Feeling cold
- Candesartan cilexetil side effect: Feeling cold
- Cardizem side effect: Feeling cold
- Chlorthalidone side effect: Feeling cold
- Clonidine side effect: Feeling cold
- Clonidine hydrochloride side effect: Feeling cold
- Cozaar side effect: Feeling cold
- Diltiazem hydrochloride side effect: Feeling cold
- Diovan side effect: Feeling cold
- Diovan hct side effect: Feeling cold
- Doxazosin mesylate side effect: Feeling cold
- Dyazide side effect: Feeling cold
- Enalapril maleate side effect: Feeling cold
- Exforge side effect: Feeling cold
- Felodipine side effect: Feeling cold
- Furosemide side effect: Feeling cold
- Hctz side effect: Feeling cold
- Hydralazine hydrochloride side effect: Feeling cold
- Hydrochlorothiazide side effect: Feeling cold
- Hyzaar side effect: Feeling cold
- Indapamide side effect: Feeling cold
- Inderal side effect: Feeling cold
- Irbesartan side effect: Feeling cold
- Labetalol hydrochloride side effect: Feeling cold
- Lasix side effect: Feeling cold
- Lipitor side effect: Feeling cold
- Lisinopril side effect: Feeling cold
- Lisinopril and hydrochlorothiazide side effect: Feeling cold
- Lopressor side effect: Feeling cold
- Losartan side effect: Feeling cold
- Losartan potassium side effect: Feeling cold
- Losartan potassium; hydrochlorothiazide side effect: Feeling cold
- Lotrel side effect: Feeling cold
- Metoprolol succinate side effect: Feeling cold
- Metoprolol tartrate side effect: Feeling cold
- Micardis side effect: Feeling cold
- Micardis hct side effect: Feeling cold
- Nifedipine side effect: Feeling cold
- Norvasc side effect: Feeling cold
- Olmesartan medoxomil side effect: Feeling cold
- Perindopril erbumine side effect: Feeling cold
- Propranolol hydrochloride side effect: Feeling cold
- Quinapril side effect: Feeling cold
- Ramipril side effect: Feeling cold
- Spironolactone side effect: Feeling cold
- Telmisartan side effect: Feeling cold
- Tenormin side effect: Feeling cold
- Toprol-xl side effect: Feeling cold
- Triamterene and hydrochlorothiazide side effect: Feeling cold
- Valsartan side effect: Feeling cold
- Vasotec side effect: Feeling cold
- Verapamil hcl side effect: Feeling cold
- Verapamil hydrochloride side effect: Feeling cold
- Zestril side effect: Feeling cold
- Ziac side effect: Feeling cold
- Zide side effect: Feeling cold
Related publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol (the active ingredients of Coreg) and Coreg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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