Coreg and Periorbital oedema - a phase IV clinical study of FDA data

Summary:

Periorbital oedema is reported as a side effect among people who take Coreg (carvedilol), especially for people who are female, 60+ old, also take Lasix, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Periorbital oedema when taking Coreg. It is created by eHealthMe based on reports of 48,155 people who have side effects when taking Coreg from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Periorbital oedema?

Periorbital oedema (swelling around the eyes) is found to be associated with 549 drugs and 655 conditions by eHealthMe. Check the latest studies of Periorbital oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

48,155 people reported to have side effects when taking Coreg.
Among them, 31 people (0.06%) have Periorbital oedema.

Among these 31 people:

What is the gender of people who have Periorbital oedema when taking Coreg? *

female: 85.19 %
male: 14.81 %

What is the age of people who have Periorbital oedema when taking Coreg? *

What are other drugs people take besides Coreg? *

What are other side effects people have besides Periorbital oedema? *

Anaemia (lack of blood): 13 people, 41.94%
Oedema Peripheral (superficial swelling): 12 people, 38.71%
Cardiac Failure Congestive: 12 people, 38.71%
Fatigue (feeling of tiredness): 11 people, 35.48%
Diarrhea: 9 people, 29.03%
Weight Increased: 8 people, 25.81%
Cardiac Valve Disease (heart valve disease): 8 people, 25.81%
Weakness: 8 people, 25.81%
Nausea And Vomiting: 8 people, 25.81%
Dyspnea (difficult or laboured breathing): 7 people, 22.58%

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 9 people, 29.03%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 16.13%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 4 people, 12.90%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.68%
Chronic Kidney Disease: 3 people, 9.68%
Gastrointestinal Stromal Tumor: 3 people, 9.68%
Nausea (feeling of having an urge to vomit): 3 people, 9.68%
Indigestion: 2 people, 6.45%
Cardiac Disorder: 2 people, 6.45%
Pain: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Coreg and have Periorbital oedema?

- Check whether Periorbital oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coreg:

Coreg (49,583 reports)

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Periorbital oedema:

Periorbital oedema (549 drugs)

Browse all the conditions that are associated with Periorbital oedema:

Periorbital oedema (655 conditions)

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Coreg) and Coreg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.