Coreg and Sinus arrhythmia - a phase IV clinical study of FDA data

Summary:

Sinus arrhythmia is reported as a side effect among people who take Coreg (carvedilol), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Aspirin, and have Pain.

The phase IV clinical study analyzes which people have Sinus arrhythmia when taking Coreg. It is created by eHealthMe based on reports of 48,155 people who have side effects when taking Coreg from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Sinus arrhythmia?

Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle) is found to be associated with 368 drugs and 418 conditions by eHealthMe. Check the latest studies of Sinus arrhythmia.

On Jul, 15, 2026

48,155 people reported to have side effects when taking Coreg.
Among them, 23 people (0.05%) have Sinus arrhythmia.

Among these 23 people:

How long have people been on Coreg when they have Sinus arrhythmia? *

What is the gender of people who have Sinus arrhythmia when taking Coreg? *

female: 50 %
male: 50 %

What is the age of people who have Sinus arrhythmia when taking Coreg? *

What are other drugs people take besides Coreg? *

What are other side effects people have besides Sinus arrhythmia? *

Stress And Anxiety: 11 people, 47.83%
Chest Pain: 10 people, 43.48%
Dizziness: 10 people, 43.48%
Weakness: 8 people, 34.78%
Pleural Effusion (water on the lungs): 8 people, 34.78%
Dyspnea (difficult or laboured breathing): 8 people, 34.78%
Enlarged Heart: 7 people, 30.43%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 30.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 30.43%
Oedema Peripheral (superficial swelling): 7 people, 30.43%

What are the existing conditions these people have? *

Pain: 5 people, 21.74%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 3 people, 13.04%
Heart Rate Irregular: 3 people, 13.04%
Blood Uric Acid Increased: 3 people, 13.04%
Depression: 3 people, 13.04%
Phosphorus Metabolism Disorder: 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 13.04%
High Blood Cholesterol: 3 people, 13.04%
Joint Pain: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

Do you take Coreg and have Sinus arrhythmia?

- Check whether Sinus arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coreg:

Coreg (49,583 reports)

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus arrhythmia:

Sinus arrhythmia (368 drugs)

Browse all the conditions that are associated with Sinus arrhythmia:

Sinus arrhythmia (418 conditions)

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Coreg) and Coreg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.