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Coreg and Toxic encephalopathy - a phase IV clinical study of FDA data

Summary:

Toxic encephalopathy is reported as a side effect among people who take Coreg (carvedilol), especially for people who are female, 60+ old, also take Lisinopril, and have Back pain.

The phase IV clinical study analyzes which people have Toxic encephalopathy when taking Coreg. It is created by eHealthMe based on reports of 48,155 people who have side effects when taking Coreg from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Toxic encephalopathy?

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) is found to be associated with 424 drugs and 616 conditions by eHealthMe. Check the latest studies of Toxic encephalopathy.

On Jul, 10, 2026

48,155 people reported to have side effects when taking Coreg.
Among them, 14 people (0.03%) have Toxic encephalopathy.

Could Coreg cause Toxic encephalopathy?

Among these 14 people:

What is the gender of people who have Toxic encephalopathy when taking Coreg? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Toxic encephalopathy when taking Coreg? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 90.91 %

What are other drugs people take besides Coreg? *

  1. Lisinopril: 9 people, 64.29%
  2. Acetaminophen: 8 people, 57.14%
  3. Ambien: 8 people, 57.14%
  4. Lasix: 8 people, 57.14%
  5. Aspirin: 7 people, 50.00%
  6. Xanax: 7 people, 50.00%
  7. Magnesium: 7 people, 50.00%
  8. Ondansetron Hydrochloride: 5 people, 35.71%
  9. Paroxetine Hydrochloride: 5 people, 35.71%
  10. Simvastatin: 3 people, 21.43%

What are other side effects people have besides Toxic encephalopathy? *

  1. Cardiac Arrest: 9 people, 64.29%
  2. Hypotension (abnormally low blood pressure): 8 people, 57.14%
  3. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 8 people, 57.14%
  4. Acute Kidney Failure: 8 people, 57.14%
  5. Arrhythmias (irregular heartbeat): 8 people, 57.14%
  6. Dehydration (dryness resulting from the removal of water): 8 people, 57.14%
  7. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 8 people, 57.14%
  8. Low Cardiac Output Syndrome (decreased cardiac output): 7 people, 50.00%
  9. Leukocytosis (increased white blood cells): 7 people, 50.00%
  10. Hypernatraemia (an abnormally high plasma concentration of sodium ions): 7 people, 50.00%

What are the existing conditions these people have? *

  1. Weight Loss: 1 person, 7.14%
  2. Rash Pruritic (redness with itching): 1 person, 7.14%
  3. Prostate Cancer Metastatic: 1 person, 7.14%
  4. Normal Pressure Hydrocephalus (a neurological disorder in which there is too much cerebrospinal fluid in the ventricles of the brain): 1 person, 7.14%
  5. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 1 person, 7.14%
  6. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 7.14%
  7. High Blood Cholesterol: 1 person, 7.14%
  8. Gastric Disorder (disease of stomach): 1 person, 7.14%
  9. Depression: 1 person, 7.14%
  10. Back Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Coreg and have Toxic encephalopathy?

- Check whether Toxic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coreg:

Toxic encephalopathy treatments and more:

How severe was Toxic encephalopathy and when was it recovered:

Expand to all the drugs that have ingredients of carvedilol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toxic encephalopathy:

Browse all the conditions that are associated with Toxic encephalopathy:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Coreg) and Coreg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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