Cosopt and Encephalitis - a phase IV clinical study of FDA data

Summary:

Encephalitis is reported as a side effect among people who take Cosopt (dorzolamide hydrochloride; timolol maleate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Xalatan, and have Uveitis.

The phase IV clinical study analyzes which people have Encephalitis when taking Cosopt. It is created by eHealthMe based on reports of 8,872 people who have side effects when taking Cosopt from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Encephalitis?

Encephalitis (inflammation of the brain) is found to be associated with 655 drugs and 847 conditions by eHealthMe. Check the latest studies of Encephalitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

8,872 people reported to have side effects when taking Cosopt.
Among them, 11 people (0.12%) have Encephalitis.

Among these 11 people:

How long have people been on Cosopt when they have Encephalitis? *

What is the gender of people who have Encephalitis when taking Cosopt? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Encephalitis when taking Cosopt? *

What are other drugs people take besides Cosopt? *

What are other side effects people have besides Encephalitis? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 27.27%
Neurological Symptom (symptoms of nervous system disease): 3 people, 27.27%
Chickenpox (infection with varicella zoster virus): 3 people, 27.27%
Cerebellar Atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements): 2 people, 18.18%
Acute Hepatic Failure: 2 people, 18.18%
Upper Extremity Mass: 1 person, 9.09%
Pneumonia Herpes Viral (herpes simplex virus pneumonia:): 1 person, 9.09%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1 person, 9.09%
Neck Pain: 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%

What are the existing conditions these people have? *

Uveitis (inflammation of the uvea): 4 people, 36.36%
Hypokalemia (low potassium): 3 people, 27.27%
Urinary Tract Infection: 3 people, 27.27%
Tachycardia Paroxysmal (a form of tachycardia which begins and ends in an acute (or paroxysmal) manner): 3 people, 27.27%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 27.27%
Peripheral Swelling: 3 people, 27.27%
Dizziness: 3 people, 27.27%
Gout (uric acid crystals building up in the body): 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Hypoacusis (loss of hearing): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Cosopt and have Encephalitis?

- Check whether Encephalitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cosopt:

Cosopt (9,029 reports)

Encephalitis treatments and more:

Encephalitis (9,372 reports)

How severe was Encephalitis and when was it recovered:

Encephalitis in Cosopt

Expand to all the drugs that have ingredients of dorzolamide hydrochloride; timolol maleate:

Encephalitis and drugs with ingredients of dorzolamide hydrochloride; timolol maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Encephalitis:

Encephalitis (655 drugs)

Browse all the conditions that are associated with Encephalitis:

Encephalitis (847 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride; timolol maleate (the active ingredients of Cosopt) and Cosopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.